Evidence map›Paper›PMID 40769724›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

Pre- and Post-synaptic Mechanisms of Neuronal Inhibition Assessed Through Biochemically Detailed Modeling of GABA

Tuomo Mäki-Marttunen, Jan Fredrik Kismul, Kadri Pajo, Jan Michael Schulz, Tiina Manninen, Gaute T Einevoll, Marja-Leena Linne, Ole A Andreassen, Jeanette Hellgren Kotaleski

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Potential TMS biomarkers for GABAAlcohol, clinical & experimental research · 2025
    Pooled it
  2. From Atoms to Neuronal Spikes: A Multiscale Simulation Framework.Journal of chemical theory and computation · 2026
    Review
  3. From Atoms to Neuronal Spikes: A Multi-Scale Simulation Framework.bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tuomo Mäki-MarttunenFaculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland tuomo.maki-marttunen@tuni.fi.ORCID 0000-0002-7082-2507
Jan Fredrik KismulFaculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland.
Kadri PajoDepartment of Neuroscience, Karolinska Institutet, Solna 171 77, Sweden.ORCID 0000-0003-2110-7889
Jan Michael SchulzDepartment of Biomedicine, University of Basel, Basel 4031, Switzerland.ORCID 0000-0003-1557-5352
Tiina ManninenFaculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland.ORCID 0000-0002-0456-1185
Gaute T EinevollDepartment of Physics, Norwegian University of Life Sciences, Ås 1432, Norway.ORCID 0000-0002-5425-5012
Marja-Leena LinneFaculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland.
Ole A AndreassenCentre for Precision Psychiatry, Institute of Clinical Medicine, University of Oslo, Oslo 0424, Norway.ORCID 0000-0002-4461-3568
Jeanette Hellgren KotaleskiDepartment of Neuroscience, Karolinska Institutet, Solna 171 77, Sweden.ORCID 0000-0002-0550-0739

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GABA

Indexed as

Models, NeurologicalNeural InhibitionNeuronsReceptors, GABA-BSignal TransductionSynapsesAnimalsCA1 Region, HippocampalComputer SimulationG Protein-Coupled Inwardly-Rectifying Potassium ChannelsMaleMicePatch-Clamp TechniquesPyramidal CellsRatsRGS ProteinsG Protein-Coupled Inwardly-Rectifying Potassium ChannelsReceptors, GABA-BRGS ProteinsCA1 pyramidal cellsGIRK channelslayer V pyramidal cellsmass-action-law-based modelingmulticompartmental modelingN-type Ca2+ channelsRGS proteinsshort-term depressionsubcellular-level neuron modelling

Identifiers

PMID40769724
PMCPMC12410044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.