Evidence map›Paper›PMID 40768860›Full record

ArticleCell calcium2025

Calmodulin enhancement of mitochondrial calcium uniporter function in isolated mitochondria.

Sara A Garcia, Anne M Neumaier, Michael Kohlhaas, Anton Xu, Alexander Nickel, Katharina J Ermer, Luzia Enzner, Christoph Maack, Vasco Sequeira, Christopher N Johnson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell calcium, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Neurotoxic mechanisms of cadmium in neurodegenerative diseases.Frontiers in cell and developmental biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sara A GarciaDepartment of Chemistry Mississippi State University, Starkville MS 39759 USA.
Anne M NeumaierComprehensive Heart Failure Center, University Clinic Wurzburg, Am Schwarzenberg 15, 97078 Wurzburg, Germany.
Michael KohlhaasComprehensive Heart Failure Center, University Clinic Wurzburg, Am Schwarzenberg 15, 97078 Wurzburg, Germany.
Anton XuComprehensive Heart Failure Center, University Clinic Wurzburg, Am Schwarzenberg 15, 97078 Wurzburg, Germany.
Alexander NickelComprehensive Heart Failure Center, University Clinic Wurzburg, Am Schwarzenberg 15, 97078 Wurzburg, Germany.
Katharina J ErmerComprehensive Heart Failure Center, University Clinic Wurzburg, Am Schwarzenberg 15, 97078 Wurzburg, Germany.
Luzia EnznerComprehensive Heart Failure Center, University Clinic Wurzburg, Am Schwarzenberg 15, 97078 Wurzburg, Germany.
Christoph MaackComprehensive Heart Failure Center, University Clinic Wurzburg, Am Schwarzenberg 15, 97078 Wurzburg, Germany.
Vasco SequeiraComprehensive Heart Failure Center, University Clinic Wurzburg, Am Schwarzenberg 15, 97078 Wurzburg, Germany. Electronic address: Sequeira_v@ukw.de.
Christopher N JohnsonDepartment of Chemistry Mississippi State University, Starkville MS 39759 USA. Electronic address: cn.johnson@chemistry.msstate.edu.

Funding

Calcium modification of voltage gated sodium channelsR35GM142868 · NIGMS · MISSISSIPPI STATE UNIVERSITY · PI JOHNSON, CHRISTOPHER N. · 2021 to 2025
$2.0M
NIGMS NIH HHS R35 GM142868
6 · The paper itself

Abstract

Mitochondrial calcium (Ca

Indexed as

CalciumCalcium ChannelsCalmodulinMitochondriaAnimalsMiceCalciumCalcium ChannelsCalmodulinmitochondrial calcium uniporterCalciumCalmodulinCalmodulin dependent kinase II (CaMKII)Mitochondrial calcium uniporter (MCU)Permeability transition pore (PTP)

Identifiers

PMID40768860
PMCPMC13281459

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.