Evidence map›Paper›PMID 40768588›Full record

ArticleScience advances2025

Atomistic mechanism of noncanonical voltage gating in K

Yessenbek K Aldakul, Marcus Schewe, Carlos Coll-Diez, Songhwan Hwang, Thomas Baukrowitz, Han Sun

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yessenbek K AldakulResearch Section of Chemical Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), 13125 Berlin, Germany.ORCID 0000-0002-9686-9899
Marcus ScheweInstitute of Physiology, Kiel University, 24118 Kiel, Germany.ORCID 0000-0002-6192-5651
Carlos Coll-DiezInstitute of Physiology, Kiel University, 24118 Kiel, Germany.ORCID 0009-0009-3121-0725
Songhwan HwangResearch Section of Chemical Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), 13125 Berlin, Germany.ORCID 0000-0003-4323-1450
Thomas BaukrowitzInstitute of Physiology, Kiel University, 24118 Kiel, Germany.ORCID 0000-0003-4562-0505
Han SunResearch Section of Chemical Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), 13125 Berlin, Germany.ORCID 0000-0002-1655-0838

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In classical voltage-gated cation channels, the movement of a voltage-sensing domain (VSD) opens a gate in the pore domain. However, two-pore domain K

Indexed as

Ion Channel GatingPotassium Channels, Tandem Pore DomainBinding SitesHumansMolecular Dynamics SimulationPatch-Clamp TechniquesPotassiumPotassiumPotassium Channels, Tandem Pore Domain

Identifiers

PMID40768588
PMCPMC12327462

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.