Evidence map›Paper›PMID 40768576›Full record

ArticleScience advances2025

Simultaneous imaging of bidirectional guided waves probes arterial mechanical anisotropy, blood pressure, and stress synchronously.

Yuxuan Jiang, Guo-Yang Li, Keshuai Hu, Shiyu Ma, Yang Zheng, Mingwei Jiang, Zhaoyi Zhang, Xinyu Wang, Yanping Cao

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Feel the force: Biomechanical homeostasis of the cardiovascular system.Journal of translational internal medicine · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuxuan JiangInstitute of Biomechanics and Medical Engineering, AML, Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China.ORCID 0000-0001-7660-8029
Guo-Yang LiDepartment of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing 100871, China.ORCID 0000-0002-5939-9293
Keshuai HuInstitute of Biomechanics and Medical Engineering, AML, Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China.
Shiyu MaInstitute of Biomechanics and Medical Engineering, AML, Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China.
Yang ZhengInstitute of Biomechanics and Medical Engineering, AML, Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China.ORCID 0000-0003-3321-9677
Mingwei JiangInstitute of Biomechanics and Medical Engineering, AML, Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China.ORCID 0009-0006-7103-4875
Zhaoyi ZhangInstitute of Biomechanics and Medical Engineering, AML, Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China.ORCID 0000-0001-9191-3451
Xinyu WangDepartment of Cardiology, Peking University Third Hospital, Beijing 100191, China.ORCID 0000-0002-7895-2031
Yanping CaoInstitute of Biomechanics and Medical Engineering, AML, Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China.ORCID 0000-0003-4787-9748

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arterial biomechanical indicators have long been recognized as fundamental contributors to the physiology and pathology of cardiovascular systems. Probing multiple biomechanical parameters of arteries simultaneously throughout the cardiac cycle is highly important but remains challenging. Here, we report a method to quantify arterial anisotropic stiffness, arterial wall stresses, and local blood pressure in a single measurement. With programmed ultrasound excitation and imaging, arterial axial and circumferential guided waves were simultaneously induced and measured in the longitudinal view. Then, a mechanical model was proposed to quantitatively predict the correlation of arterial guided waves with arterial biomechanical parameters. Our experimental design and biomechanical model enable an elastography method to assess temporal variations in blood pressure, bidirectional stiffness, and mechanical stresses in arterial walls. In vivo experiments were performed on healthy young, normotensive older, and hypertensive older volunteers. The results demonstrate that our method can find applications in understanding aging of cardiovascular system and diagnosis of cardiovascular diseases.

Indexed as

ArteriesBlood PressureStress, MechanicalAdultAgedAnisotropyBiomechanical PhenomenaElasticity Imaging TechniquesFemaleHumansHypertensionMaleMiddle AgedVascular Stiffness

Identifiers

PMID40768576
PMCPMC12327456

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.