Evidence map›Paper›PMID 40768504›Full record

ArticleHealth informatics journal

A secondary data analysis on hypotheses generated by inexperienced clinical researchers: Cases from a randomized controlled study.

Mytchell A Ernst, Brooke N Draghi, James J Cimino, Vimla L Patel, Yuchun Zhou, Jay H Shubrook, Sonsoles De Lacalle, Aneesa Weaver, Chang Liu, Xia Jing

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Health informatics journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Co-Occurrence ofInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Mytchell A ErnstDepartment of Public Health Sciences, College of Behavioral, Social and Health Sciences, Clemson University, Clemson, SC, USA.
Brooke N DraghiDepartment of Public Health Sciences, College of Behavioral, Social and Health Sciences, Clemson University, Clemson, SC, USA.
James J CiminoDepartment of Biomedical Informatics and Data Science, Heersink School of Medicine, The University of Alabama at Birmingham, AL, USA.ORCID 0000-0003-4101-1622
Vimla L PatelCognitive Studies in Medicine and Public Health, The New York Academy of Medicine, New York City, NY, USA.
Yuchun ZhouPatton College of Education, Ohio University, Athens, OH, USA.
Jay H ShubrookDepartment of Clinical Sciences and Community Health, Touro University California College of Osteopathic Medicine, Vallejo, CA, USA.
Sonsoles De LacalleDepartment of Health Science, California State University Channel Islands, Camarillo, CA, USA.
Aneesa WeaverDepartment of Public Health Sciences, College of Behavioral, Social and Health Sciences, Clemson University, Clemson, SC, USA.
Chang LiuRuss College of Engineering and Technology, Ohio University, Athens, OH, USA.
Xia JingDepartment of Public Health Sciences, College of Behavioral, Social and Health Sciences, Clemson University, Clemson, SC, USA.ORCID 0000-0002-1916-4588

Funding

Tissue Structural and Neural Remodeling in Human Sacroiliac JointP20GM121342 · NIGMS · CLEMSON UNIVERSITY · PI Hai Yao · 2018 to 2026
$24.7M
SC Biomedical Informatics & Data Science for Health Impact (SC BIDS4Health)T15LM013977 · NLM · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Alexander V Alekseyenko, Brian Dean · 2022 to 2026
$1.2M
Exploration of the hypothesis-generation process as guided by secondary data analysis in clinical research: Can the process be more efficient?R15LM012941 · NLM · OHIO UNIVERSITY ATHENS · PI JING, XIA · 2018 to 2018
$394k
NIGMS NIH HHS P20 GM121342NLM NIH HHS R15 LM012941NLM NIH HHS T15 LM013977
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Data AnalysisResearch PersonnelAdultFemaleHumansMaleRandomized Controlled Trials as TopicSecondary Data Analysiscase studyclinical researchresearch designscientific hypothesis generation

Identifiers

PMID40768504
PMCPMC13282015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.