Evidence map›Paper›PMID 40768370›Full record

ArticleJournal of studies on alcohol and drugs2026

Investing in Infrastructure: A Mixed-Methods Cost Analysis of Implementation Strategies to Address Emerging Youth Drug Trends.

Andria B Eisman, Jacob Whitman, Suzanne Brown, Erica Richardson, Christina Holmes, Tracy Robinson, Barry Schmidt, Eric Swihart, Bo Kim

Abstract read
In one paragraph

Article in Journal of studies on alcohol and drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andria B EismanDivision of Kinesiology, Health, and Sport Studies, College of Education, Wayne State University, Detroit, Michigan.
Jacob WhitmanDepartment of Economics, Wayne State University, Detroit, Michigan.
Suzanne BrownSchool of Social Work, Wayne State University, Detroit, Michigan.
Erica RichardsonDivision of Kinesiology, Health, and Sport Studies, College of Education, Wayne State University, Detroit, Michigan.
Christina HolmesEaton Regional Education Service Agency, Charlotte, Michigan.
Tracy RobinsonTuscola Intermediate School District, Caro, Michigan.
Barry SchmidtBay-Arenac Intermediate School District, Bay City, Michigan.
Eric SwihartJackson County Intermediate School District, Jackson, Michigan.
Bo KimCenter for Health and Implementation Research, VA Boston Healthcare System, Boston, Massachusetts.

Funding

Enhancing the Impact of Evidence-Based Prevention for Youth: The Rapid Adaption to Prevent Drug Use (RAPD) Implementation StrategyR34DA056777 · NIDA · WAYNE STATE UNIVERSITY · PI EISMAN, ANDRIA B · 2022 to 2024
$693k
NIDA NIH HHS R34 DA056777
6 · The paper itself

Abstract

objectiveSchools engaged in prevention efforts struggle to respond quickly and effectively to changing drug use trends due to insufficient investment in infrastructure at local, state, and national levels. This results in preventable morbidity and mortality among adolescents. This study estimated the costs associated with implementing Rapid Adaptation to Prevent Drug use (RAPD) infrastructure-building implementation strategies, using mixed methods to optimize data collection feasibility and quality and to support a comprehensive understanding of outcomes.

methodWe conducted semi-structured interviews in Step 1 (pre-pilot trial) to inform the initial cost data collection approach. In Step 2, we used activity-based costing, conducted a sensitivity analysis, and estimated the budget impacts of replication. Step 3 included interviews with pilot participants to contextualize the results and verify time reporting.

resultsThirty-four school personnel participated in Step 1 interviews, and four health coordinators and six teachers participated in the pilot study. We identified cost drivers and pragmatic constraints related to effective time-cost data collection and developed an activity-based costing data collection plan. The estimated cost of deploying RAPD (Step 2) was $6,215/school. We estimated the budget impact of replication to be $5,551/school, with 52% of the cost incurred during the pre-implementation phase. In Step 3 interviews, participants identified financial and staffing resources as central challenges to infrastructure development.

conclusionsThis study used a mixed-methods approach, incorporating an exploratory sequential design, to proactively guide microcosting. By identifying potential barriers in advance, we enhanced the rigor and feasibility of the data collection process. This study provides preliminary cost estimates for deploying RAPD infrastructure-building strategies to address emerging drug trends and sustain prevention efforts.

Indexed as

School Health ServicesSchoolsSubstance-Related DisordersAdolescentCosts and Cost AnalysisFemaleHumansMalePilot Projects

Identifiers

PMID40768370
PMCPMC12981700

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.