Evidence map›Paper›PMID 40768193›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2025

Improving Diabetes and Pre-Diabetes Detection in the UK: Insights From HbA1c Screening in an Acute Hospital's Emergency Department.

Edward B Jude, Sushant Saluja, Adrian Heald, Dono Widiatmoko, Nicolaas Schaper, Simon G Anderson

Registry-linked trialAbstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04653545 (FINDing Patients With Unknown Diabetes During Acute Medical Admission in a District General Hospital In Tameside), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04653545 completednot on this map

FINDing Patients With Unknown Diabetes During Acute Medical Admission in a District General Hospital In Tameside (FIND-IT)

TypeobservationalSponsorTameside General HospitalRan2022 to 2025Enrolled5,050ConditionsDiabete Type 2ArmsHbA1c
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edward B JudeDepartment of Endocrinology, Tameside and Glossop Integrated Care, NHS Foundation Trust, Ashton-under-Lyne, UK. Edward.Jude@tgh.nhs.uk.ORCID http://orcid.org/0000-0002-3186-4122
Sushant SalujaDivision of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Adrian HealdDivision of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0002-9537-4050
Dono WidiatmokoCollege of Health, Psychology and Social Care, University of Derby, Derby, UK.
Nicolaas SchaperResearch Schools CARIM and CAPHRI, Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Simon G AndersonDivision of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMany individuals in the community have undiagnosed glucose intolerance, type 2 diabetes (T2D), and pre-diabetes (Pre-DM). This study explored screening for unknown glucose intolerance in the emergency department (ED) in an acute hospital.

methods1382 persons attending the ED without T2D were screened using HbA1c. T2D and Pre-DM were classified using American Diabetes Association (ADA) and National Institute for Health and Care Excellence (NICE) criteria. The Finnish Diabetes Risk Score (FINDRISC) was calculated in all patients.

resultsAccording to NICE criteria, 80.1% (1107 individuals) exhibited normal glucose tolerance, 11.6% (160 individuals) exhibited pre-diabetes, and 8.3% (115 individuals) exhibited diabetes. Each unit increase in FINDRISC score, using multinomial regression, corresponded to an 8% (5-12%; p < 0.001) higher risk for pre-diabetes and a 16% (10-23%; p < 0.001) higher risk for diabetes (NICE). The risk remained elevated even after adjusting for age, sex, and ethnicity. South-Asians had higher glucose intolerance rates than white British (34.8% versus 18.5%) using the NICE criteria, and even greater at 50.0% versus 37.6% using ADA criteria. The adjusted relative risk of having pre-diabetes in people of color compared with white British individuals was 1.77 (1.04-3.00; p = 0.034, ADA) and 2.84 (1.41-5.65; p = 0.003, NICE). The multinomial relative-risk ratio (RRRs) for having diabetes by ethnicity was 2.97 (1.73-5.08; p < 0.0001, ADA) and 2.80 (1.59-4.94; p < 0.0001, NICE).

conclusionsRoutine HbA1c screening in the ED, with FINDRISC scoring, successfully identifies individuals with diabetes and pre-diabetes. This approach could enable early intervention, particularly in groups at higher risk of glucose intolerance.

trial registrationClinicalTrials.gov identifier, NCT04653545.

Indexed as

Cost-effectivenessEmergency departmentEthnic disparitiesFINDRISCHbA1c screeningPre-diabetesType 2 diabetesUndiagnosed diabetes

Identifiers

PMID40768193
PMCPMC12474847

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.