ArticleSleep & breathing = Schlaf & Atmung2025
Association between skin temperature variability and sleep apnea severity: findings from a pilot study.
Article in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Sleep Disordered Breathing Severity Alters Overnight Temperature Changes in Children.Journal of sleep research · 2026Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeObstructive sleep apnea (OSA) may disrupt autonomic and vascular control, affecting skin temperature variability (STV). We aimed to assess whether STV (measured at distal and proximal sites) is associated with OSA severity (apnea-hypopnea index [AHI] and percent of sleep time with oxygen saturation below 90% [T90]) and if STV can aid in non-invasive OSA risk screening.
methodsEighteen participants underwent two nights of polysomnography with simultaneous distal and proximal skin temperature recording using iButtons. STV was calculated by standard deviation, median absolute deviation, and Poincaré plot analyses for sleep onset-to-offset, non-rapid eye movement (NREM), rapid eye movement (REM), and wake intervals. Linear mixed-effect models assessed relationships between STV and AHI/T90. Mediation analysis evaluated the role of body mass index (BMI), and receiving-operator-characteristic-curve (ROC)-based analysis assessed the screening potential of STV for moderate-to-severe OSA. All p-values were adjusted by the Benjamini-Hochberg False Discovery Rate (FDR).
resultsAHI showed a strong, negative association with distal STV during NREM sleep, especially median absolute deviation (fixed effect coefficient = - 8.16, FDR-adjusted p < 0.001). T90 was similarly associated (- 1.90, FDR-adjusted p < 0.01). No significant relationships were found during REM or wake. BMI did not mediate these associations. ROC analysis revealed high discriminative ability for moderate-to-severe OSA (AUC: 0.93-0.97).
conclusionReduced distal STV during NREM sleep independently signals OSA severity and may serve as a promising, non-invasive biomarker for screening OSA risk.
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Registered trials
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