Evidence map›Paper›PMID 40768130›Full record

ArticleIndian journal of pediatrics2026

Multilinguistic Validation of IMPACT-III Instrument to Assess Quality of Life of Indian Children with Inflammatory Bowel Disease.

Arjun Parihar, Rohan Malik, Anshu Srivastava, Bhaswati Chakrabarti Acharyya, Malathi Sathiyasekaran, Neelam Mohan, Rishi Bolia, Ujjal Poddar, Moinak Sen Sharma, Shivani Deswal and 1 more

Abstract readValidation StudyMulticenter Study
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Article in Indian journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Arjun PariharDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Rohan MalikDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi, India. dr.rohanmalik@gmail.com.ORCID 0000-0003-3450-9668
Anshu SrivastavaDepartment of Pediatric Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Bhaswati Chakrabarti AcharyyaDepartment of Pediatric Gastroenterology, Institute of Child Health, Kolkata, India.
Malathi SathiyasekaranDepartment of Pediatric Gastroenterology, Rainbow Children's Hospital, Chennai, India.
Neelam MohanDepartment of Pediatric Gastroenterology, Hepatology and Liver Transplantation, Medanta-The Medicity, Gurgaon, India.
Rishi BoliaDepartment of Pediatric Gastroenterology, All India Institute of Medical Sciences, Rishikesh, India.
Ujjal PoddarDepartment of Pediatric Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Moinak Sen SharmaDepartment of Pediatric Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Shivani DeswalDepartment of Pediatric Gastroenterology, Hepatology and Liver Transplantation, Medanta-The Medicity, Gurgaon, India.
Pooja SemwalDepartment of Pediatric Gastroenterology, All India Institute of Medical Sciences, Rishikesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo validate the disease-specific quality of life (QoL) instrument for pediatric inflammatory bowel disease (PIBD) patients in three Indian languages (Hindi, Tamil and Bengali). Additionally, also to reveal the significant factors which effect QoL of PIBD patients in India.

methodsOne hundred and two (102) PIBD patients (mean age 13 ± 2.59 y) across 6 centres were enrolled. Each child completed two questionnaires - the IMPACT-III and Paediatric Quality of Life Inventory Version 4.0 Generic Core Scale (PedsQL™) - in one of the three languages. A uniform clinico-demographic proforma was completed for each recruit to reveal factors which determine QoL. During analysis authors used Cronbach's alpha for internal consistency, principal component analysis for factor analysis, Spearman's correlation between the questionnaires for concurrent validity and ANOVA analysis between IMPACT-III health-related quality of life (HRQoL) scores and disease severity to establish discriminant validity.

resultsA five-domain structure was most suitable: 'Concerns', 'Social acceptance', 'Mental disposition', 'Disease adjustment' & 'Self-confidence', with good internal reliability (Cronbach's α = 0.73-0.94). Concurrent and discriminant validity of the new questionnaire was also statistically significant (p < 0.001). Higher monthly family income led to better QoL scores in the 'Concerns' (p = 0.04) and 'Disease adjustment' (p = 0.03) domains while children with ulcerative colitis (UC) had better 'Social acceptance' scores than children with Crohn's disease (CD) (p = 0.02).

conclusionsModified IMPACT-III questionnaire with a five-domain structure demonstrated good validity and reliability for Indian population. 'Social acceptance' was higher in patients with ulcerative colitis. There is a favourable impact of higher family income on 'Concerns' and 'Disease adjustment' in PIBD.

Indexed as

Inflammatory Bowel DiseasesQuality of LifeAdolescentChildFemaleHumansIndiaMalePsychometricsReproducibility of ResultsSeverity of Illness IndexSurveys and QuestionnairesChildrenCrohn diseaseIndiaInflammatory bowel diseaseQuality of lifeQuestionnaireUlcerative colitisValidation

Identifiers

PMID40768130

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