Evidence map›Paper›PMID 40768066›Full record

ReviewIntensive care medicine2025

Extracorporeal life support for adult patients with ARDS.

Alain Combes, Alexander Supady, Darryl Abrams, Cara Agerstrand, Jenelle Badulak, Luigi Camporota, Eddy Fan, Niall D Ferguson, John F Fraser, Carol Hodgson and 8 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Intensive care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. CRRT and ECMO: one love or separate lives?Intensive care medicine · 2026
    Article
  5. ECMO for patients needing surgery.Intensive care medicine · 2026
    Article
  6. Minimally invasive extracorporeal COCritical care (London, England) · 2026
    Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Alain Combes *Institute of Cardiometabolism and Nutrition, Sorbonne Université INSERM Unité Mixte de Recherche (UMRS) 1166, Paris, France.ORCID 0000-0002-6030-3957
Alexander Supady *Interdisciplinary Medical Intensive Care, Faculty of Medicine, Medical Center-University of Freiburg, University of Freiburg, Freiburg im Breisgau, Germany.ORCID 0000-0003-4056-3652
Darryl AbramsDivision of Pulmonary, Allergy and Critical Care Medicine, NewYork-Presbyterian / Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0001-9073-3897
Cara AgerstrandDivision of Pulmonary, Allergy and Critical Care Medicine, NewYork-Presbyterian / Columbia University Irving Medical Center, New York, NY, USA.
Jenelle BadulakDepartment of Emergency Medicine, Division of Pulmonary Critical Care and Sleep Medicine, Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA.
Luigi CamporotaDepartment of Adult Critical Care, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID 0000-0001-5600-1676
Eddy FanInterdepartmental Division of Critical Care Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Niall D FergusonInterdepartmental Division of Critical Care Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-6213-5264
John F FraserCritical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.ORCID 0000-0002-7012-2519
Carol HodgsonAustralian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, VIC, Australia.
Samir JaberDepartment of Anaesthesiology and Critical Care Medicine B (DAR B), PhyMed Exp, INSERM U1046 Montpellier, Saint-Eloi Hospital, University Teaching Hospital of Montpellier, University of Montpellier, Montpellier, France.
Graeme MacLarenCardiothoracic ICU, National University Hospital, Singapore, Singapore.ORCID 0000-0002-1307-4274
Brijesh V PatelDivision of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, London, UK.
Giles J PeekDepartment of Surgery, Congenital Heart Center, University of Florida, Gainesville, FL, USA.ORCID 0000-0002-1313-6498
Matthieu SchmidtInstitute of Cardiometabolism and Nutrition, Sorbonne Université INSERM Unité Mixte de Recherche (UMRS) 1166, Paris, France.ORCID 0000-0002-2931-4412
Kiran ShekarUniversity of Queensland, Brisbane, Australia.
Arthur S SlutskyInterdepartmental Division of Critical Care Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-6063-3876
Daniel Brodie *Division of Pulmonary and Critical Care Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, USA. DanielBrodie@jhu.edu.ORCID 0000-0002-0813-3145

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracorporeal Life Support (ECLS), including venovenous (VV) extracorporeal membrane oxygenation (ECMO) and extracorporeal carbon dioxide removal (ECCO2R) is a temporary support option for patients with severe respiratory failure. Current data and recent guidelines support the use of VV ECMO for select patients with very severe respiratory failure as this technique might improve survival in appropriately selected patients. Patient selection criteria, timing of ECMO initiation and optimal management of mechanical ventilation and anticoagulation, and other adjunctive treatment options are a matter of ongoing research.

Indexed as

Extracorporeal Membrane OxygenationRespiratory Distress SyndromeAdultCarbon DioxideHumansRespiration, ArtificialCarbon DioxideAcute respiratory distress syndromeARDSECCO2RECLSExtracorporeal carbon dioxide removalExtracorporeal life supportVenovenous extracorporeal membrane oxygenationVV ECMO

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.