Evidence map›Paper›PMID 40767988›Full record

ArticleJournal of epidemiology and global health2025

Towards Rabies Elimination in Pakistan: Barriers, Facilitators, and the Role of One Health.

Anum Shaikh, Shifa Salman Habib, Ali Faisal Saleem, Naseem Salahuddin

Abstract read
In one paragraph

Article in Journal of epidemiology and global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anum ShaikhDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan. anum.shaikh22@alumni.aku.edu.
Shifa Salman HabibDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.ORCID http://orcid.org/0000-0002-4531-8472
Ali Faisal SaleemDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.ORCID http://orcid.org/0000-0003-1804-9868
Naseem SalahuddinDepartment of Infectious Diseases, Indus Hospital & Health Network (IHHN), Karachi, Pakistan.ORCID http://orcid.org/0000-0003-0566-5872

Funding

MBBS '88 Student and Trainee Initiated Research (STIR)- ROUND#3 141
6 · The paper itself

Abstract

backgroundRabies is a neglected zoonotic disease with an estimated 59,000 deaths annually, disproportionately affecting low- and middle-income countries. Pakistan remains a high-burden setting due to weak surveillance, poor intersectoral coordination, and limited public awareness. Therefore, this study aimed to examine the barriers and facilitators to rabies control in Pakistan through the One Health approach, integrating perspectives from both community members and institutional stakeholders.

methodsThis mixed-methods study design was conducted in Karachi, where 385 household respondents completed a structured Knowledge, Attitudes, and Practices (KAP) survey, and 10 stakeholders (out of 14 approached) were interviewed across human, animal, and environmental sectors. The survey tool was adapted from previously validated instruments and pilot-tested. Thematic analysis was conducted using a deductive framework based on One Health principles. The quantitative data were analyzed descriptively using IBM SPSS Statistics 21, whereas the qualitative data were analyzed using Atlas.ti.

resultsThe average knowledge score was 5.54 out of 13 (42.6%), indicating substantial knowledge gaps among community members. Key barriers identified included limited vaccine availability, inadequate surveillance systems, fragmented dog population control, and weak multisectoral collaboration. Enabling factors included stakeholder willingness, local Trap-Neuter-Vaccinate-Release (TNVR) initiatives, and existing collaborative frameworks. Stakeholder awareness of the One Health approach was present but lacked institutional translation.

conclusionA coordinated, One Health-based strategy for rabies elimination is urgently needed in Pakistan that addresses both systemic and community-level gaps through sustained advocacy, stronger intersectoral coordination, expansion of TNVR initiatives, and establishment of centralized surveillance for bite incidents and post-exposure management.

Indexed as

Disease EradicationHealth Knowledge, Attitudes, PracticeOne HealthRabiesRabies VaccinesAdultAnimalsDogsFemaleHumansMaleMiddle AgedPakistanSurveys and QuestionnairesYoung AdultZoonosesRabies VaccinesMass dog vaccinationOne HealthPakistanRabies controlTNVRZoonotic Diseases

Identifiers

PMID40767988
PMCPMC12328853

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.