Evidence map›Paper›PMID 40767987›Full record

ReviewThe Saudi dental journal2025

Temporomandibular joint disorder related to cancer metastasis: A review on reported cases in the literature.

Hamed Mortazavi, Anita Taheri, Sara Alehossein, Mehdi Hashemi

Abstract readReview
In one paragraph

Review in The Saudi dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hamed MortazaviDepartment of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-0778-5299
Anita TaheriSina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-8805-2600
Sara AlehosseinSchool of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0009-0001-3340-340X
Mehdi HashemiDental Research Center, Mazandaran University of Medical Sciences, Sari, Iran. mehdi_hashemi@sbmu.ac.ir.ORCID http://orcid.org/0009-0007-4936-5536

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMetastasis to the temporomandibular joint is an uncommon clinical entity that often mimics benign temporomandibular disorders, leading to diagnostic challenges. This systematic review aimed to consolidate the existing literature on temporomandibular joint metastasis to delineate its clinical and demographic characteristics, diagnostic pitfalls, and treatment approaches.

methodsA comprehensive search was conducted across PubMed/MEDLINE, Scopus, and Embase electronic databases. Two independent reviewers screened the titles, abstracts, and full texts of 3,659 articles, ultimately selecting 47 articles encompassing 55 reported cases.

resultsThe analysis revealed a mean patient age of 61.8 ± 13.99 years, with a slight female predominance. Lung and breast cancers were the most common primary sites, with adenocarcinoma being the predominant histopathological type. Clinically, pain, swelling, and restricted mouth opening were the most frequently observed symptoms, although a subset of patients presented with atypical features. Notably, in 49% of cases, TMJ metastasis was detected prior to the diagnosis of the primary malignancy. Multimodal treatment, incorporating combinations of chemotherapy, radiotherapy, and surgery, was the most common therapeutic approach.

Indexed as

AdenocarcinomaCancerMetastasisTemporomandibular Joint

Identifiers

PMID40767987
PMCPMC12328852

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.