SynthesisEchocardiography (Mount Kisco, N.Y.)2025
Applications of Speckle Tracking Echocardiography in Stress Echocardiography: A Systematic Review on Feasibility, Diagnostic, and Clinical Utility.
Synthesis in Echocardiography (Mount Kisco, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Applications of Speckle Tracking Echocardiography in Stress Echocardiography: A Systematic Review on Feasibility, Diagnostic, and Clinical Utility.Echocardiography (Mount Kisco, N.Y.) · 2025Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis review evaluates the applications of speckle-tracking echocardiography (STE) in stress echocardiography, focusing on feasibility, physiological adaptations, and its diagnostic and prognostic utility in cardiovascular conditions.
methodsA systematic search of PubMed identified studies published up to December 28, 2024, using terms related to STE, stress echocardiography, and myocardial strain. Grey literature was excluded. Eligible studies assessed myocardial strain under stress conditions and reported on feasibility, diagnostic accuracy, or prognostic outcomes.
resultsSixty-four studies were included, covering healthy individuals, athletes, at-risk populations, and patients with cardiovascular conditions. Feasibility studies demonstrated high interobserver reliability, with strain parameters measurable in > 80% of cases (intraclass correlation coefficient [ICC] 0.80 to 0.92). In healthy individuals and athletes, STE revealed myocardial adaptations and exercise-induced changes. In at-risk populations, such as those with diabetes or after cardiotoxic therapies, STE identified subclinical myocardial dysfunction, facilitating early intervention. For coronary artery disease (CAD) and heart failure (HF), stress-induced changes in global and segmental strain improved diagnostic accuracy and risk stratification, with thresholds such as a > 15% reduction in global longitudinal strain under stress aiding therapeutic decision-making.
conclusionsSTE enhances the diagnostic and prognostic utility of stress echocardiography by providing reproducible strain parameters and facilitating early detection of dysfunction in high-risk populations. Future research should focus on standardizing strain analysis and integrating artificial intelligence (AI) to optimize clinical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.