Evidence map›Paper›PMID 40767253›Full record

ArticleAnatomia, histologia, embryologia2025

Morphological, Histochemical and Immunohistochemical Characterisation of the Penis in Free-Ranging Giant Anteaters (Myrmecophaga tridactyla).

Fernanda Barthelson Carvalho de Moura, Victor Gustavo Santos Môra, Natalia Camargo Faraldo, Gabriel Correa de Camargo, Carlos Roberto Teixeira, Maria Valeria de Toledo Rodovalho, Tatiane Terumi Negrão Watanabe, Daniel Felipe Barrantes Murillo, Noeme Sousa Rocha, Carlos Eduardo Fonseca-Alves

Abstract read
In one paragraph

Article in Anatomia, histologia, embryologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fernanda Barthelson Carvalho de Moura *School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.ORCID https://orcid.org/0000-0002-8153-2038
Victor Gustavo Santos Môra *Institute of Health Sciences, Paulista University (UNIP), Bauru, Brazil.
Natalia Camargo FaraldoSchool of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.
Gabriel Correa de CamargoSchool of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.
Carlos Roberto TeixeiraSchool of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.
Maria Valeria de Toledo RodovalhoInstitute of Health Sciences, Paulista University (UNIP), Bauru, Brazil.
Tatiane Terumi Negrão WatanabeAntech Diagnostics, Mars Petcare Science and Diagnostics, Fountain Valley, California, USA.
Daniel Felipe Barrantes MurilloDepartment of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma, USA.
Noeme Sousa RochaInstitute of Health Sciences, Paulista University (UNIP), Bauru, Brazil.
Carlos Eduardo Fonseca-AlvesSchool of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 302977/2021-0Morris Animal Foundation D21ZO-601
6 · The paper itself

Abstract

The giant anteater (Myrmecophaga tridactyla) belongs to the superorder Xenarthra and is distributed throughout Central and South America. This animal is listed as 'vulnerable' on the International Union for Conservation of Nature's Red List of Threatened Species. Studies on the reproduction of this species are essential because of its peculiarities; however, there is a lack of information on its reproductive aspects and the biotechnologies that can be applied to it. Morphological and histopathological descriptions of the reproductive organs of Myrmecophaga tridactyla are fundamental for determining the general characteristics that could improve our understanding of reproductive disorders in this species. Therefore, this study aimed to perform morphological and histochemical characterisation of the penis of Myrmecophaga tridactyla. For this purpose, we collected six postmortem samples of giant anteater penises. The penis of the giant anteater has no foreskin, two erectile bodies, a paired corpora cavernosa, corpus spongiosum and urethra. Type I (red) and type III (yellow-green) collagen fibres were distributed throughout the stroma and erectile bodies of the penis. Periodic acid-Schiff (PAS)-positive staining was observed in the epithelial cells at the base of the hair follicles, and immunohistochemical immunolabelling for androgen receptors (AR) and oestrogen receptors (ER) was detected in all cells of the transitional epithelium of the penile urethra. These findings suggest that penile urethra cells are sensitive to oestrogen and progesterone.

Indexed as

PenisXenarthraAnimalsCollagenImmunohistochemistryMaleCollagenanteaterbackground lesionhistopathologyimmunohistochemistrymale genitalia

Identifiers

PMID40767253
PMCPMC12326516

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.