Evidence map›Paper›PMID 40767209›Full record

ArticleInternational journal of health policy and management2025

Selecting Cost-Effectiveness Methods for Health Benefits Package Design: A Systematic Approach.

Cassandra Nemzoff, Sedona Sweeney, Rob Baltussen, Anna Vassall

Abstract read
In one paragraph

Article in International journal of health policy and management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cassandra NemzoffLondon School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0003-2735-0644
Sedona SweeneyLondon School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0003-4233-9080
Rob BaltussenRadboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-8364-2847
Anna VassallLondon School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-2911-1375

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCost-effectiveness (CE) is a common prioritization criterion in health benefits package (HBP) design. However, to assess CE is a time- and data-demanding process, so most HBP exercises rely wholly or partially on global evidence. Extensive investment has been made in analyses, models, and tools to support cost-effectiveness analyses (CEAs) for HBPs. However, little attention has been paid to how national HBP assessors should both understand and select CE estimates. A structured, national process to select assessment methods is essential for ensuring the accuracy, ownership, and transparency of HBP design. This can be supported by "adaptive" health technology assessment (aHTA) principles, which focus on structured methodological choices based on the time, data, and capacity available. The objective of this paper was to apply aHTA framing to CEA methods selection for HBPs, and to make recommendations on how countries may consider systematically making these choices going forward.

methodsWe first reviewed the definitions and categorization of different aHTA methods. We then conducted a scoping review of previous HBP assessments to understand how CEA methods used in HBPs fit into the aHTA framework, and a follow-up survey of authors to fill gaps. Results of the literature review and survey were interpreted and narratively synthesized.

resultsWe found that previous HBP assessments used four aHTA methods, sometimes simultaneously: expert opinion (n=3/20), review (n=12/20), model adaptation (n=6/20), and new model (n=2/20). The literature review and survey found that aHTA methods for HBPs take between 1-13 months; require different data sources depending on the method(s) used; and generally, require capacity in health economics, medicine, public health, and CE modelling. We supplement our report with a discussion of key considerations for methods selection.

conclusionTrading off time, data, and capacity needs for different CE assessment methods can help to support structured, local design of HBP assessments.

Indexed as

Cost-Benefit AnalysisTechnology Assessment, BiomedicalHumansCost-EffectivenessEconomic EvaluationHealth Benefits PackageHealth Technology Assessment

Identifiers

PMID40767209
PMCPMC12089834

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.