Evidence map›Paper›PMID 40766914›Full record

ReviewFrontiers in pediatrics2025

The mouth or the nose: the past, present, and future of ultra-slim gastroscopy of the upper gastrointestinal tract in pediatrics.

Paul Tran, Rose Lee, Ali Mencin, Matthew Ryan, Joel A Friedlander, Michael A Manfredi

Abstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paul TranDivision of Pediatric Gastroenterology, Phoenix Children's Hospital, Phoenix, AZ, United States.
Rose LeeDivision of Pediatric Gastroenterology, The Medical College of Wisconsin, Wisconsin, WI, United States.
Ali MencinDivision of Pediatric Gastroenterology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States.
Matthew RyanDivision of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Joel A FriedlanderEvoEndo, Inc., Centennial, CO, United States.
Michael A ManfrediDivision of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ultra-slim, flexible endoscopy pioneered for the evaluation of luminal diseases of the airway, has been used for over 40 years. In the late 20th century, it was adopted in the gastrointestinal specialties for evaluation of the digestive tract with and without the need for sedation. Since the advent of this technology, numerous descriptions of its use in small anatomic areas have been described. These include stricture evaluation and therapy, ostomy evaluation, biliary interventions, and diagnostic endoscopic evaluation of pediatric patients. This manuscript reviews the availability and clinical utility of ultra-slim flexible endoscopes, describes technical approaches, and highlights the potential value the technology offers to pediatric providers and healthcare systems. Methods: A comprehensive literature review was conducted on the use of ultra-slim endoscopes in the pediatric and adult gastroenterology. Expert discussions were held to evaluate current practices, indications, and equipment. The resulting expert opinion was generated to summarize pertinent information regarding key techniques, indications, and practical considerations for implementation in pediatric settings. Results: Although ultra-slim endoscopes started their use in small-space adult gastroenterology procedures, they have shown significant benefit and value within pediatrics. The literature documents their use in both sedated and unsedated environments, including transnasal upper endoscopy, variceal surveillance, esophageal stricture evaluation, neonatal endoscopy, enteral tube placement, and ostomy assessment. Conclusion: Ultra-slim flexible endoscopy provides pediatric gastroenterologists with a valuable diagnostic and therapeutic tool. When used appropriately, either with or without sedation, it has the potential to increase clinical efficiency, reduce procedural risk, and improve access to care.

Indexed as

endoscopygastroenterologypediatricstransnasal endoscopyultra-slimultrathin

Identifiers

PMID40766914
PMCPMC12321853

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.