Evidence map›Paper›PMID 40766860›Full record

ArticleInternational journal of general medicine2025

Combination of iLux Photothermal Pulsation Therapy with 0.05% Cyclosporine in the Treatment of Meibomian Gland Dysfunction: A Clinical Study.

Hongliang Xu, Qian Kang

Abstract read
In one paragraph

Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hongliang XuDepartment of Ophthalmology, Aidi Eye Hospital, Chengdu, Sichuan, People's Republic of China.
Qian KangDepartment of Ophthalmology, Aidi Eye Hospital, Chengdu, Sichuan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study is to investigate the effect of iLux with 0.05% cyclosporine in the treatment of meibomian gland dysfunction. Methods and Materials: In retrospective analysis, 72 patients of meibomian gland dysfunction were selected and divided into combination groups according to different treatment methods (n=32, iLux + 0.05% cyclosporine ophthalmic fluid) and the conventional group (n=44, 0.05% cyclosporine ophthalmic fluid). Compare the two groups of baseline data and clinical efficacy difference, compare the two groups after treatment eye symptoms, eye surface disease index score change. Results: Overall response rate of the combined group was higher than the conventional group (P <0.05). Post-treatment, both groups were improved differently (P <0.05), however, in the combined group, ocular symptom score, ocular surface disease index, conjunctival congestion score, corneal fluorescent staining score, meibomian gland (ostium condition score, lipid secretion shape score, deletion score) and interleukin-6, interleukin-1 β were all lower than those in the conventional group, The non-invasive mean tear film break-up time (NIBUTav), non-invasive first tear film break-up time (NIBUTf) and tear meniscus height in the combined group were higher than the conventional group (P <0.05). Conclusion: ILux meibomian gland photothermal pulsation complex therapy instrument combined with 0.05% cyclosporine ophthalmic solution for the treatment of meibomian gland dysfunction.

Indexed as

cyclosporine ophthalmic solutioniLux eyelid gland photothermal pulsatile compound therapy instrumentmeibomian gland dysfunctionpatientstreatment effect

Identifiers

PMID40766860
PMCPMC12324061

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.