Evidence map›Paper›PMID 40766840›Full record

ArticleFrontiers in cellular and infection microbiology2025

Assessing the potential impact of salidroside on Chikungunya virus-induced acute interstitial nephritis via network pharmacology, molecular docking and

Sheng Cheng, Jialiang Xin, Tianran Zhang, Yulin Zhang, Chengxi Ji, Lulu Kang, Xiangyu Zhu, He Zhang, Wei Wang, Xinfei Liao

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In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Current issues in molecular biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sheng ChengKey Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Jialiang XinKey Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Tianran ZhangWenzhou Municipal Center for Disease Control and Prevention, Wenzhou Municipal Institute of Health Supervision, Wenzhou, China.
Yulin ZhangThe Humanities Laboratory for Ecological Civilization and Environmental Governance of Zhejiang Province, Institute of Virology, Wenzhou University, Wenzhou, China.
Chengxi JiThe Humanities Laboratory for Ecological Civilization and Environmental Governance of Zhejiang Province, Institute of Virology, Wenzhou University, Wenzhou, China.
Lulu KangThe Humanities Laboratory for Ecological Civilization and Environmental Governance of Zhejiang Province, Institute of Virology, Wenzhou University, Wenzhou, China.
Xiangyu ZhuThe Humanities Laboratory for Ecological Civilization and Environmental Governance of Zhejiang Province, Institute of Virology, Wenzhou University, Wenzhou, China.
He ZhangChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Wei WangThe Humanities Laboratory for Ecological Civilization and Environmental Governance of Zhejiang Province, Institute of Virology, Wenzhou University, Wenzhou, China.
Xinfei LiaoWenzhou Polytechnic, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chikungunya virus (CHIKV) infection is often linked to acute interstitial nephritis (AIN) in fatal cases. Given the global spread of CHIKV and the lack of targeted antiviral treatments, there is an urgent need for effective therapeutic strategies against CHIKV-induced AIN. This study explored the therapeutic potential of salidroside (Sal) using an integrative approach involving network pharmacology, molecular docking and

Indexed as

Antiviral AgentsChikungunya FeverChikungunya virusGlucosidesNephritis, InterstitialPhenolsApoptosisCell SurvivalHEK293 CellsHumansMolecular Docking SimulationNetwork PharmacologyVirus ReplicationAntiviral AgentsGlucosidesPhenolsrhodiolosideapoptosisCHIKVferroptosismolecular dockingnetwork pharmacologysalidroside

Identifiers

PMID40766840
PMCPMC12321764

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.