Evidence map›Paper›PMID 40766788›Full record

ArticleFood science & nutrition2025

Quercetin Improves Lipopolysaccharide-Induced Septic Liver Injury by Inhibiting the Activation of ROCK/NF-κB/NLRP3 Pathway.

Lina Xiao, Lingya Kong, Ming Han, Jianing Zhao, Meini Zhang, Yanjin Li, Mingxuan Wang, Zirui Wang, Jiaxuan Li, Zhihong Ma and 1 more

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lina XiaoCollege of Integrative Medicine Hebei University of Chinese Medicine Shijiazhuang Hebei China.
Lingya KongEmergency Department The Third Hospital of Hebei Medical University (Xiangjiang District) Shijiazhuang Hebei China.
Ming HanCollege of Integrative Medicine Hebei University of Chinese Medicine Shijiazhuang Hebei China.
Jianing ZhaoCollege of Integrative Medicine Hebei University of Chinese Medicine Shijiazhuang Hebei China.
Meini ZhangCollege of Integrative Medicine Hebei University of Chinese Medicine Shijiazhuang Hebei China.
Yanjin LiCollege of Basic Medicine Hebei University of Chinese Medicine Shijiazhuang Hebei China.
Mingxuan WangCollege of Basic Medicine Hebei University of Chinese Medicine Shijiazhuang Hebei China.
Zirui WangCollege of Basic Medicine Hebei University of Chinese Medicine Shijiazhuang Hebei China.
Jiaxuan LiCollege of Basic Medicine Hebei University of Chinese Medicine Shijiazhuang Hebei China.
Zhihong MaCollege of Integrative Medicine Hebei University of Chinese Medicine Shijiazhuang Hebei China.ORCID https://orcid.org/0000-0001-9989-9578
Zhuojun DengEmergency Department The Third Hospital of Hebei Medical University (Xiangjiang District) Shijiazhuang Hebei China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quercetin (QUE) is a common flavonoid compound, found in fruits and vegetables, with powerful anti-inflammatory and antioxidant properties. Nevertheless, the protective function and mechanisms of QUE in septic liver injury (SLI) caused by lipopolysaccharide (LPS) are still unknown. This study aimed to investigate the effect of QUE on SLI rats and the underlying mechanisms. Forty male Sprague-Dawley (SD) rats were randomly assigned into four groups (

Indexed as

lipopolysaccharideNLRP3 inflammasomequercetinrho kinase (ROCK)septic liver injury

Identifiers

PMID40766788
PMCPMC12321602

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.