Evidence map›Paper›PMID 40766776›Full record

ArticleIEEE access : practical innovations, open solutions2025

OXSeg: Multidimensional Attention UNet-Based Lip Segmentation Using Semi-Supervised Lip Contours.

Hanie Moghaddasi, Christina Chambers, Sarah N Mattson, Jeffrey R Wozniak, Claire D Coles, Raja Mukherjee, Michael Suttie

Abstract read
In one paragraph

Article in IEEE access : practical innovations, open solutions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hanie MoghaddasiNuffield Department of Women's and Reproductive Health, University of Oxford, OX3 9DU Oxford, U.K.ORCID 0009-0004-7895-2893
Christina ChambersDepartment of Pediatrics, University of California at San Diego, La Jolla, CA 92093, USA.
Sarah N MattsonDepartment of Psychology, Center for Behavioral Teratology, San Diego State University, San Diego, CA 92182, USA.ORCID 0000-0001-8499-9605
Jeffrey R WozniakDepartment of Psychiatry and Behavioral Sciences, University of Minnesota at Twin Cities, Minneapolis, MN 55414, USA.ORCID 0000-0002-7132-8519
Claire D ColesDepartment of Psychiatry and Behavioral Sciences, School of Medicine, Emory University, Atlanta, GA 30322, USA.
Raja MukherjeeFaculty of Health and Medical Science, Medical School, University of Surrey, GU2 7XH Guildford, U.K.ORCID 0000-0002-2171-928X
Michael SuttieNuffield Department of Women's and Reproductive Health, University of Oxford, OX3 9DU Oxford, U.K.ORCID 0000-0002-5538-8431

Funding

FASD in San Diego and Moscow (U01 Research Project)U01AA014834 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI SARAH N MATTSON WELLER · 2003 to 2026
$12.4M
Whole Body Effects of PAE Across the Life Span: Early Markers of & Clinical Interventions for Children and Adolescents in UkraineU01AA014835 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHRISTINA CHAMBERS · 2003 to 2026
$12.1M
Image Analysis of Neurofacial Effects of Prenatal AlcoholExposureU01AA014809 · NIAAA · UNIVERSITY OF OXFORD · PI Michael Suttie · 2007 to 2026
$5.8M
Fetal Alcohol Spectrum Disorders in Adults: Health and NeurobehaviorU01AA026108 · NIAAA · EMORY UNIVERSITY · PI Tamara Sonia Bodnar, Claire D. Coles · 2017 to 2026
$3.9M
tDCS and cognitive training as a neurodevelopmental intervention in FASDU01AA030164 · NIAAA · UNIVERSITY OF MINNESOTA · PI Jeffrey Robert Wozniak · 2022 to 2026
$2.2M
Multi-modal connectivity methods for the validation of Fetal Alcohol Spectrum Disorder diagnostic criteriaU01AA026102 · NIAAA · UNIVERSITY OF MINNESOTA · PI WOZNIAK, JEFFREY ROBERT · 2017 to 2021
$1.7M
NIAAA NIH HHS U01 AA014809NIAAA NIH HHS U01 AA014834NIAAA NIH HHS U01 AA014835NIAAA NIH HHS U01 AA026102NIAAA NIH HHS U01 AA026108NIAAA NIH HHS U01 AA030164
6 · The paper itself

Abstract

Lip segmentation plays a crucial role in various domains, such as lip synchronization, lip-reading, and diagnostics. However, the effectiveness of supervised lip segmentation is constrained by the availability of lip contour in the training phase. A further challenge with lip segmentation is its reliance on image quality, lighting, and skin tone, leading to inaccuracies in the detected boundaries. To address these challenges, we propose a sequential lip segmentation method that integrates attention UNet and multidimensional input. We unravel the micro-patterns in facial images using local binary patterns to build multidimensional inputs. Subsequently, the multidimensional inputs are fed into sequential attention UNets, where the lip contour is reconstructed. We introduce a mask generation method that uses a few anatomical landmarks and estimates the complete lip contour to improve segmentation accuracy. This mask has been utilized in the training phase for lip segmentation. To evaluate the proposed method, we use facial images to segment the upper lips and subsequently assess lip-related facial anomalies in subjects with fetal alcohol syndrome (FAS). Using the proposed lip segmentation method, we achieved a mean dice score of 84.75%, and a mean pixel accuracy of 99.77% in upper lip segmentation. To further evaluate the method, we implemented classifiers to identify those with FAS. Using a generative adversarial network (GAN), we reached an accuracy of 98.55% in identifying FAS in one of the study populations. This method could be used to improve lip segmentation accuracy, especially around Cupid's bow, and sheds light on distinct lip-related characteristics of FAS.

Indexed as

Attention UNetfetal alcohol syndromelip segmentationmask generationmultidimensional inputssequential networks

Identifiers

PMID40766776
PMCPMC12323439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.