Evidence map›Paper›PMID 40766673›Full record

ArticlebioRxiv : the preprint server for biology2025

SEAL : Spatially-resolved Embedding Analysis with Linked Imaging Data.

Simon Warchol, Grace Guo, Johannes Knittel, Dan Freeman, Usha Bhalla, Jeremy L Muhlich, Peter K Sorger, Hanspeter Pfister

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Dan Freeman
Usha Bhalla
Hanspeter PfisterORCID 0000-0002-3620-2582

Funding

Enhancing Assisted Reproductive Technologies with Deep Learning and Data VisualizationR01HD104969 · NICHD · HARVARD UNIVERSITY · PI BEN YOSEF, DALIT, NEEDLEMAN, DANIEL · 2021 to 2025
$3.4M
Visual Analytics for Exploration and Hypothesis Generation Using Highly MultiplexedSpatial Data of Tissues and TumorsU01CA284207 · NCI · HARVARD MEDICAL SCHOOL · PI PFISTER, HANSPETER, SANTAGATA, SANDRO · 2023 to 2025
$1.4M
NCI NIH HHS U01 CA284207NICHD NIH HHS R01 HD104969
6 · The paper itself

Abstract

Dimensionality reduction techniques help analysts make sense of complex, high-dimensional spatial datasets, such as multiplexed tissue imaging, satellite imagery, and astronomical observations, by projecting data attributes into a two-dimensional space. However, these techniques typically abstract away crucial spatial, positional, and morphological contexts, complicating interpretation and limiting insights. To address these limitations, we present

Identifiers

PMID40766673
PMCPMC12324231

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.