Evidence map›Paper›PMID 40766589›Full record

ArticlebioRxiv : the preprint server for biology2025

EphA2 and Ephrin-A1 Utilize the Same Interface for Both

Soyeon Kim, Paul Toth, Wei Wang, Elena Seiradake, Xiaojun Shi, Bingcheng Wang

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Soyeon KimDivision of Cancer Biology, Department of Medicine, MetroHealth Center for Cancer Research, MetroHealth Campus, Case Western Reserve University, Cleveland, OH, United States.
Paul TothDepartment of Chemistry & Biochemistry, Ohio State University, Columbus, OH, Unites States.
Wei WangDivision of Cancer Biology, Department of Medicine, MetroHealth Center for Cancer Research, MetroHealth Campus, Case Western Reserve University, Cleveland, OH, United States.
Elena SeiradakeDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.
Xiaojun ShiDivision of Cancer Biology, Department of Medicine, MetroHealth Center for Cancer Research, MetroHealth Campus, Case Western Reserve University, Cleveland, OH, United States.
Bingcheng WangDivision of Cancer Biology, Department of Medicine, MetroHealth Center for Cancer Research, MetroHealth Campus, Case Western Reserve University, Cleveland, OH, United States.

Funding

RESEARCH ONCOLOGY TRAINING GRANTT32CA059366 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI JACKSON, MARK W. · 1993 to 2025
$5.5M
(PQ1) HIV-infected T-cell exosomes in lung cancer progressionR01CA250067 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI JIN, GE, WANG, BINGCHENG · 2020 to 2024
$3.7M
Targeting EphA2 in GlioblastomaR01NS096956 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI WANG, BINGCHENG · 2016 to 2021
$2.6M
EphA1 homotypic and EphA1-EphA2 heterotypic interactions in cell regulationR01CA297778 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI ELENA B PASQUALE, Bingcheng Wang · 2025 to 2026
$1.4M
NCI NIH HHS R01 CA250067NCI NIH HHS R01 CA297778NCI NIH HHS T32 CA059366NINDS NIH HHS R01 NS096956
6 · The paper itself

Abstract

The 14 members of Eph receptor tyrosine kinases (RTK) bind to membrane-tethered ligand called ephrins and mediate cell contact signaling where the receptors and ligands engage

Identifiers

PMID40766589
PMCPMC12324522

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.