Evidence map›Paper›PMID 40766562›Full record

ArticlebioRxiv : the preprint server for biology2025

Human bladder organoids model urinary tract infection and bacteriophage therapy.

Jacob J Zulk, Clare M Robertson, Samantha Ottinger, Amal Kambal, Alejandra Rivera Tostado, Rachel C Fleck, Allyson E Shea, Cristian Coarfa, Sarah E Blutt, Anthony W Maresso and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jacob J ZulkDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-3758-5503
Clare M RobertsonDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0003-1915-9495
Samantha OttingerDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0003-3439-6376
Amal KambalDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Alejandra Rivera TostadoDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.ORCID 0009-0002-9571-1763
Rachel C FleckDepartment of Microbiology and Immunology, University of South Alabama, Mobile, AL, USA.
Allyson E SheaDepartment of Microbiology and Immunology, University of South Alabama, Mobile, AL, USA.ORCID 0000-0003-1329-3888
Cristian CoarfaDepartment of Molecular and Cellular Biology, Baylor College of Medicine.ORCID 0000-0002-4183-4939
Sarah E BluttDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Anthony W MaressoDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-4452-3490
Kathryn A PatrasDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0003-2631-8810

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Suzanne AW Fuqua · 2007 to 2026
$73.9M
Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Hashem B El-Serag · 2001 to 2026
$28.3M
Translational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Cheryl L. Walker · 2019 to 2026
$14.7M
Organoid Cultivation CoreU19AI157981 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI LEMON, KATHERINE PAIGE · 2021 to 2025
$12.4M
HIGH THROUGHPUT NGS SEQUENCER AT THE BCM GENOMIC AND RNA PROFILING CORES10OD036427 · OD · BAYLOR COLLEGE OF MEDICINE · PI KRAUSHAAR, DANIEL · 2024 to 2024
$600k
Single Cell Spatial Transcriptomics Shared Instrument at the BCM Core FacilityS10OD032189 · OD · BAYLOR COLLEGE OF MEDICINE · PI CHEN, RUI · 2022 to 2022
$304k
Characterizing the impact of maternal immune response to urinary tract infection on preterm birthF31HD111236 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI OTTINGER, SAMANTHA · 2023 to 2025
$149k
Investigating Type 2 Diabetic Vaginal Microbiota and Susceptibility to a Urogenital PathogenF31DK138748 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Clare Marie Robertson · 2024 to 2026
$149k
Investigating phage therapy for the treatment of urinary tract infectionsF31DK136201 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI ZULK, JACOB JEFFREY · 2023 to 2024
$97k
NCI NIH HHS P30 CA125123NIAID NIH HHS U19 AI157981NICHD NIH HHS F31 HD111236NIDDK NIH HHS F31 DK136201NIDDK NIH HHS F31 DK138748NIDDK NIH HHS P30 DK056338NIEHS NIH HHS P30 ES030285NIH HHS S10 OD032189NIH HHS S10 OD036427
6 · The paper itself

Abstract

Urinary tract infections (UTIs), primarily caused by uropathogenic

Identifiers

PMID40766562
PMCPMC12324606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.