Evidence map›Paper›PMID 40766552›Full record

ArticlebioRxiv : the preprint server for biology2025

Targeted disruption of phage liquid crystalline droplets abolishes antibiotic tolerance of bacterial biofilms.

Abul K Tarafder, Miles Graham, Luke K Davis, Shawna Pratt, Jan Böhning, Pavithra Manivannan, Zhexin Wang, Camila M Clemente, Raymond J Owens, George A O'Toole and 2 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Abul K TarafderStructural Studies Division, MRC Laboratory of Molecular Biology; Francis Crick Avenue, Cambridge CB2 0QH, United Kingdom.
Miles GrahamStructural Studies Division, MRC Laboratory of Molecular Biology; Francis Crick Avenue, Cambridge CB2 0QH, United Kingdom.
Luke K DavisSchool of Mathematics, University of Edinburgh, Edinburgh, EH9 3FD, United Kingdom.
Shawna PrattDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, United States of America.
Jan BöhningStructural Studies Division, MRC Laboratory of Molecular Biology; Francis Crick Avenue, Cambridge CB2 0QH, United Kingdom.ORCID 0000-0002-6242-1041
Pavithra ManivannanStructural Studies Division, MRC Laboratory of Molecular Biology; Francis Crick Avenue, Cambridge CB2 0QH, United Kingdom.
Zhexin WangStructural Studies Division, MRC Laboratory of Molecular Biology; Francis Crick Avenue, Cambridge CB2 0QH, United Kingdom.
Camila M ClementeStructural Studies Division, MRC Laboratory of Molecular Biology; Francis Crick Avenue, Cambridge CB2 0QH, United Kingdom.
Raymond J OwensDivision of Structural Biology, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, United Kingdom.
George A O'TooleDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, United States of America.
Philip PearceDepartment of Mathematics, University College London, London, WC1H 0AY, United Kingdom.ORCID 0000-0001-5788-3826
Tanmay A M BharatStructural Studies Division, MRC Laboratory of Molecular Biology; Francis Crick Avenue, Cambridge CB2 0QH, United Kingdom.ORCID 0000-0002-0168-0277

Funding

cdiGMP regulation of Biofilm FormationR37AI083256 · NIAID · DARTMOUTH COLLEGE · PI O'TOOLE, GEORGE A. · 2014 to 2023
$4.7M
NIAID NIH HHS R37 AI083256Wellcome Trust
6 · The paper itself

Abstract

All bacterial biofilms contain an extracellular matrix rich in filamentous molecules 1 that self-associate

Identifiers

PMID40766552
PMCPMC12324354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.