Evidence map›Paper›PMID 40766480›Full record

ArticlebioRxiv : the preprint server for biology2025

Voltage Imaging with Periodic Structured Illumination.

Forest Speed, Alec Teel, Gregory L Futia, Diego Restrepo, Emily A Gibson

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Forest SpeedDepartment of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Alec TeelDepartment of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Gregory L FutiaDepartment of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Diego RestrepoDepartment of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Emily A GibsonDepartment of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0002-3436-1483

Funding

Development of 3D-FAST Optical Interface for Rapid Volumetric Neural Sensing and ModulationR01NS123665 · NINDS · UNIVERSITY OF COLORADO DENVER · PI GIBSON, EMILY, WELLE, CRISTIN G · 2021 to 2021
$2.7M
NINDS NIH HHS R01 NS123665
6 · The paper itself

Abstract

We utilize periodic structured illumination with pseudo-HiLo (pHiLo) image reconstruction for in vivo voltage imaging. We demonstrate reduced signal from out-of-focus cells, that contaminates voltage activity for in-focus cells of interest, with pHiLo compared to traditional widefield recordings taken with uniform illumination and pseudo-widefield (pWF) reconstructions. We discuss tradeoffs between signal-to-background ratio, signal-to-noise ratio and temporal resolution for pHiLo in the context of high-speed voltage imaging in awake mice.

Identifiers

PMID40766480
PMCPMC12324175

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.