ArticlebioRxiv : the preprint server for biology2025
Neural basis of self-control.
Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Self-control is the capacity to inhibit self-defeating behavior in the face of temptation. The neural basis of self-control remains elusive, due to the difficulty of disentangling self-control from value-based economic choice. To overcome this problem, we designed a novel task for monkeys that allows to identify states of high and low self-control. We found that neurons in the Supplementary Eye Field encode self-control and predict whether and when monkeys give in to temptation. This neuronal activity was present early in the trial, even preceding presentation of choice options. Our findings suggest that Supplementary Eye Field is part of a neuronal circuit exerting proactive self-control, which is crucial for selecting and maintaining the pursuit of costly goals that are beneficial in the long run.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.