Evidence map›Paper›PMID 40766429›Full record

ArticlebioRxiv : the preprint server for biology2025

Asymmetry and redundancy of STAT5 paralogs across CD8

Svetlana Ristin, Molly Dalzell, Christopher Armstrong, Nisa Ilsin, Antonio M Fontanella, Luis Nivelo, Lothar Hennighausen, John J O'Shea, Alejandro V Villarino

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Svetlana RistinDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Molly DalzellDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Christopher ArmstrongDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Nisa IlsinDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Antonio M FontanellaDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Luis NiveloDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Lothar HennighausenNational Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
John J O'SheaLymphocyte Cell Biology Section, Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.
Alejandro V VillarinoDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.ORCID 0000-0001-8068-2176

Funding

Stat transcription factors in immunoregulation and autoimmune diseaseZIAAR041159 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI O'SHEA, JOHN · 2009 to 2025
$49.3M
Tumor Biology Research ProgramP30CA240139 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Stephen D. Nimer · 2019 to 2026
$24.1M
Intramural NIH HHS ZIA AR041159NCI NIH HHS P30 CA240139
6 · The paper itself

Abstract

Fostering STAT5 signaling is key to immunotherapies that leverage CD8

Identifiers

PMID40766429
PMCPMC12324222

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.