Evidence map›Paper›PMID 40766340›Full record

ArticleClinical psychological science : a journal of the Association for Psychological Science2025

Introducing the Glutamate-Amplifies-Noradrenergic-Effects (GANE) Model to the Neurocognitive Study of Emotion-Related Impulsivity.

Matthew V Elliott, Ming Hsu, Lucina Q Uddin, Kiana Modavi, Sheri L Johnson

Abstract read
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In one paragraph

Article in Clinical psychological science : a journal of the Association for Psychological Science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matthew V ElliottDepartment of Psychology, University of California at Berkeley, Berkeley, CA, USA.
Ming HsuHaas School of Business, University of California at Berkeley, Berkeley, CA, USA.
Lucina Q UddinDepartment of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles, Los Angeles, CA, USA.
Kiana ModaviDepartment of Psychology, University of California at Berkeley, Berkeley, CA, USA.
Sheri L JohnsonDepartment of Psychology, University of California at Berkeley, Berkeley, CA, USA.

Funding

Stress-Induced Decays in Working Memory and Internalizing SymptomsR01MH110477 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI JOHNSON, SHERI L, TIMPANO, KIARA R · 2016 to 2020
$3.3M
Next Generation 3T MRI ScannerS10OD030378 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI GALLANT, JACK L · 2022 to 2022
$2.0M
Exploratory investigation of bilingualism, executive function, and brain organization in children with autismR21HD111805 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI UDDIN, LUCINA QAZI · 2023 to 2023
$432k
NICHD NIH HHS R21 HD111805NIH HHS S10 OD030378NIMH NIH HHS R01 MH110477
6 · The paper itself

Abstract

Emotion-related impulsivity (ERI) shows robust longitudinal associations with psychiatric disorders, aggression, and suicidality, yet a parsimonious account of its neurocognitive correlates has not been offered. We connect ERI with the Glutamate Amplifies Noradrenergic Effects (GANE) model, a framework describing how norepinephrine tunes "hotspots" of brain activation during heightened physiological arousal. First, we systematically reviewed studies of ERI and task-based functional MRI. Meta-analysis of significant effects yielded one cluster in right inferior frontal gyrus. 26 of 30 significant effects systematically co-localized in neuroanatomical "hotspots" in each corresponding task, in line with GANE. Second, adults recruited for a range of psychopathology (

Identifiers

PMID40766340
PMCPMC12323888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.