Evidence map›Paper›PMID 40766262›Full record

ArticleBelitung nursing journal2025

Health-related quality of life in Thai patients with hepatocellular carcinoma and its influencing factors: A cross-sectional study.

Thitiporn Pathomjaruwat, Yaowarat Matchim, Jane M Armer

Abstract read
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Article in Belitung nursing journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Thitiporn PathomjaruwatFaculty of Nursing, Thammasat University, Pathum Thani, Thailand.ORCID https://orcid.org/0009-0000-4574-1070
Yaowarat MatchimFaculty of Nursing, Thammasat University, Pathum Thani, Thailand.ORCID https://orcid.org/0000-0003-4000-7699
Jane M ArmerSinclair School of Nursing, University of Missouri, Columbia, USA.ORCID https://orcid.org/0000-0003-2473-5063

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Health-related quality of life (HRQoL) is a critical indicator in individuals with cancer. Patients diagnosed with hepatocellular carcinoma (HCC) commonly experience a decline in HRQoL due to both the progression of the disease and the adverse effects associated with treatment. Despite the high prevalence of HCC in Thailand, there is a paucity of research examining the HRQoL of Thai patients and the factors that may influence it. Objective: This study aimed to examine HRQoL in Thai patients with HCC and evaluated the relationships between disease stage, comorbidities, albumin level, functional status (FS), self-management behaviors (SMBs), and HRQoL. Methods: A correlational, cross-sectional study was conducted with 408 patients with HCC recruited from six hospitals in central Thailand between April and September 2024. Data collection included demographic and clinical information, along with the Functional Assessment of Cancer Therapy-Hepatobiliary (FACT-Hep) scale, Inventory of Functional Status-Cancer (IFS-CA), and the SMB scale for patients with HCC. All instruments were validated and reliable. Data were analyzed using descriptive statistics and multiple regression analysis. Results: Most participants were at intermediate (38.97%) or advanced (24.26%) stages of HCC. Overall HRQoL was high (mean FACT-Hep score = 147.92 ± 26.09). Disease stage, comorbidities, albumin level, FS, and SMBs were all significantly correlated with HRQoL ( Conclusion: Improving self-management behaviors, functional status, and nutritional status shows promise for enhancing HRQoL in patients with HCC. These findings can guide nurses in developing interventions to support patients with HCC and improve their quality of life.

Indexed as

albuminco-morbiditydisease stagefunctional statushealth-related quality of lifehepatocellular carcinomaself-management behaviorThailand

Identifiers

PMID40766262
PMCPMC12319692

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