Evidence map›Paper›PMID 40766252›Full record

ArticleResearch square2025

Mixed Reality (MR) Based Slit Lamp: The First Step Toward XR-Ophthalmology.

Rui Zhou, Wei-Chiang Lin, Byron L Lam, Rong Wen, Noble Amadi, Shuliang Jiao

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rui ZhouDepartment of Biomedical Engineering, Florida International University 10555 W Flagler St, Miami, FL 33174, USA.
Wei-Chiang LinDepartment of Biomedical Engineering, Florida International University 10555 W Flagler St, Miami, FL 33174, USA.
Byron L LamBascom Palmer Eye Institute, University of Miami Miller School of Medicine 163810 Ave, Miami, FL 33136.
Rong WenBascom Palmer Eye Institute, University of Miami Miller School of Medicine 163810 Ave, Miami, FL 33136.
Noble AmadiDepartment of Biomedical Engineering, Florida International University 10555 W Flagler St, Miami, FL 33174, USA.
Shuliang JiaoDepartment of Biomedical Engineering, Florida International University 10555 W Flagler St, Miami, FL 33174, USA.

Funding

Quantitative multimodal retinal imagingR01EY031492 · NEI · FLORIDA INTERNATIONAL UNIVERSITY · PI JIAO, SHULIANG · 2021 to 2024
$2.0M
NEI NIH HHS R01 EY031492
6 · The paper itself

Abstract

This study demonstrates the concept of Mixed Reality (MR) based slit lamp (MR-SLP), which can display real-time stereoscopic diagnostic images of the eye both locally and remotely, making it suitable for stereoscopic tele-ophthalmology applications. In MR-SLP, two high-resolution video cameras were mounted on the left and right viewing channels of a conventional slit lamp to capture corresponding diagnostic images in real time, which were then transmitted to multiple MR headsets via a broadcast network. The operator wears the MR headset to see the stereoscopic diagnostic images and operates the slit lamp using the MR's see-through function. The system's depth perception, a key feature inherited from the slit lamp, was quantitatively tested using a tube-threading task. The feasibility of tele-ophthalmology was evaluated across multiple sites with subjective feedback from participants. The results showed no observable differences in image quality or depth perception between local and remote sites, and ophthalmologists participated in this study reported a user experience with the MR-SLP that was comparable to a conventional slit lamp. Furthermore, the tube-threading test indicated that the time taken to complete the task was similar when using the MR-SLP compared to the direct view through the eyepieces. This study successfully demonstrates the feasibility of the MR-SLP for transmitting high-quality stereoscopic slit lamp images to multiple MR devices in real-time, without distance limitations, wherever an internet connection is available.

Identifiers

PMID40766252
PMCPMC12324598

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.