Evidence map›Paper›PMID 40766104›Full record

ArticleLaryngoscope investigative otolaryngology2025

Prognostic Utility of Controlling Nutritional Status Score in Patients With Oral Cavity Cancer.

Sheng-Wei Lo, Ku-Hao Fang, Adarsh Kudva, Chia-Hsuan Lai, Ming-Hsien Tsai, Chun-Ta Liao, Chung-Jan Kang, Cheng-Ming Hsu, Yuan-Hsiung Tsai, Ethan I Huang and 3 more

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In one paragraph

Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sheng-Wei LoDepartment of Otorhinolaryngology-Head and Neck Surgery Chang Gung Memorial Hospital Chiayi Taiwan.
Ku-Hao FangCollege of Medicine Chang Gung University Taoyuan Taiwan.ORCID https://orcid.org/0009-0000-2140-2410
Adarsh KudvaDepartment of Oral and Maxillofacial Surgery Manipal College of Dental Sciences Manipal Karnataka India.
Chia-Hsuan LaiCollege of Medicine Chang Gung University Taoyuan Taiwan.
Ming-Hsien TsaiCollege of Medicine Chang Gung University Taoyuan Taiwan.ORCID https://orcid.org/0000-0002-6877-1579
Chun-Ta LiaoCollege of Medicine Chang Gung University Taoyuan Taiwan.
Chung-Jan KangCollege of Medicine Chang Gung University Taoyuan Taiwan.ORCID https://orcid.org/0000-0002-5333-9396
Cheng-Ming HsuDepartment of Otorhinolaryngology-Head and Neck Surgery Chang Gung Memorial Hospital Chiayi Taiwan.ORCID https://orcid.org/0000-0003-3792-3784
Yuan-Hsiung TsaiCollege of Medicine Chang Gung University Taoyuan Taiwan.
Ethan I HuangDepartment of Otorhinolaryngology-Head and Neck Surgery Chang Gung Memorial Hospital Chiayi Taiwan.ORCID https://orcid.org/0000-0002-2789-189X
Geng-He ChangDepartment of Otorhinolaryngology-Head and Neck Surgery Chang Gung Memorial Hospital Chiayi Taiwan.ORCID https://orcid.org/0000-0001-5939-9747
Ming-Shao TsaiDepartment of Otorhinolaryngology-Head and Neck Surgery Chang Gung Memorial Hospital Chiayi Taiwan.
Yao-Te TsaiDepartment of Otorhinolaryngology-Head and Neck Surgery Chang Gung Memorial Hospital Chiayi Taiwan.ORCID https://orcid.org/0000-0002-2313-0890

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We evaluated the preoperative Controlling Nutritional Status (CONUT) score-comprising serum albumin, total cholesterol levels, and lymphocyte counts-as a prognostic marker in oral cavity squamous cell carcinoma (OCSCC). Methods: The research involved 352 patients with OCSCC who underwent primary surgical treatment at Chang Gung Memorial Hospital between January 2009 and December 2018. Patients were categorized based on their nutritional risk as determined by the CONUT score: 259 patients (73.6%) had a CONUT score of 0-1 (indicating normal nutrition), while 93 patients (26.4%) had a CONUT score of ≥ 2 (indicating varying degrees of undernutrition). We examined the relationships between the CONUT score, clinicopathological characteristics, and survival outcomes. Results: Higher CONUT scores (≥ 2) were significantly associated with poorer 5-year overall survival (OS) and disease-free survival (DFS) (both Conclusion: The preoperative CONUT score holds potential as a prognostic marker for patients with OCSCC undergoing surgery. The CONUT score-based nomogram could serve as a valuable tool for predicting survival outcomes in OCSCC management. Level of Evidence: IV.

Indexed as

biomarkerControlling Nutritional Status scorenomogramoral cavity cancerprognosis

Identifiers

PMID40766104
PMCPMC12322581

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.