Evidence map›Paper›PMID 40766100›Full record

ArticleJournal of pain research2025

Large-Channel Interlaminar Endoscopic Discectomy for Highly Migrated Lumbar Disc Herniation: Effectiveness and Safety.

Shicheng Zheng, Qinghua Zhao, Zongshan Hu, Haibo Li, Bin Wang, Zezhang Zhu, Yong Qiu, Xu Sun

Abstract read
In one paragraph

Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shicheng ZhengDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, People's Republic of China.
Qinghua ZhaoDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, People's Republic of China.
Zongshan HuDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, People's Republic of China.
Haibo LiDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, People's Republic of China.
Bin WangDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, People's Republic of China.
Zezhang ZhuDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, People's Republic of China.
Yong QiuDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, People's Republic of China.
Xu SunDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Highly migrated lumbar disc herniation (HM-LDH) presents a significant challenge for surgeons. This study aimed to assess the safety and clinical outcomes of large-channel interlaminar endoscopic discectomy for HM-LDH and compare it to open fenestration discectomy. Patients and Methods: Patients who underwent large-channel interlaminar endoscopic discectomy (group A) or open fenestration discectomy (group B) for HM-LDH between January 2021 and December 2023 were included. Radiological and clinical outcomes were evaluated over at least one year. Operation time, intraoperative blood loss, postoperative drainage, postoperative hospital stay, patient-reported outcomes and complications were compared between groups, independent sample Results: One hundred and thirty-six patients were retrospectively included in this study, with 84 in group A and 52 in group B, respectively. Although similar operative time was observed in group A and group B, group A was detected with significantly less intraoperative blood loss (17.6 ± 6.0 mL vs 101.7 ± 62.0 mL, P = 0.003) and shorter postoperative hospital stay (2.4 ± 0.6 days vs 5.2 ± 2.2 days, P < 0.001). Additionally, postoperative drainage was required in group B (35.9 ± 26.4 mL), but none in group A. Follow-up durations averaged 22.8 ± 4.9 months for group A and 20.2 ± 4.2 months for group B. Both groups achieved a significant improvement in VAS, ODI and EQ-5D scores without significant differences. No case experienced neurological deficits and reoperation after surgery in either group. The overall percentage of patients with good to excellent results according to modified MacNab criteria of group A was 95.2%, versus 92.3% of group B. Conclusion: For the treatment of HM-LDH, large-channel interlaminar endoscopic discectomy is an effective and safe treatment.

Indexed as

clinical effectivenesshighly migrated disc herniationopen fenestration discectomyspine endoscopy

Identifiers

PMID40766100
PMCPMC12323881

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.