Evidence map›Paper›PMID 40766020›Full record

ArticleBiomaterials research2025

Targeting ZBP1-Mediated PANoptosis: Inflammation-Responsive Selenized Chitosan Nanoparticles Loaded with Moringa A for Antiviral Pneumonia Therapy.

Wenhui Wu, Ruidong Li, Chunmei Lv, Dandan Yang, Shunqiang Song, Min Yang, Yongai Xiong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenhui WuInstitute of Chinese Pharmaceutical Preparations, Chongqing Traditional Chinese Medicine Hospital, Chongqing 400021, China.
Ruidong LiKey Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou 563000, China.
Chunmei LvKey Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou 563000, China.
Dandan YangKey Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou 563000, China.
Shunqiang SongKey Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou 563000, China.
Min YangInstitute of Chinese Pharmaceutical Preparations, Chongqing Traditional Chinese Medicine Hospital, Chongqing 400021, China.
Yongai XiongKey Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou 563000, China.ORCID https://orcid.org/0000-0002-4086-5135

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral pneumonia poses a major global public health challenge, where excessive inflammatory responses contribute to tissue damage and respiratory failure. Inflammation-responsive nanoparticles can target inflamed areas, improving drug delivery while minimizing side effects. Chitosan, a biocompatible polysaccharide with anti-inflammatory and immunomodulatory properties, gains enhanced antioxidant and anti-inflammatory capabilities when combined with selenium. This study developed selenium-chitosan nanoparticles loaded with Moringa A (MA), a natural antiviral compound from

Identifiers

PMID40766020
PMCPMC12323157

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.