ArticleAlzheimer's & dementia (Amsterdam, Netherlands)
Real-world use of diagnostic tests for mild cognitive impairment, Alzheimer's disease, and other dementias in Medicare fee-for-service beneficiaries.
Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Dementia diagnostic deserts: workforce and geographic inequities in the diagnostic pathway for cognitive impairment.Health affairs scholar · 2026Article
- Blood-based biomarkers of Alzheimer's disease: potential utility in clinical practice.Current opinion in neurology · 2026Review
- Accelerated 3D MRI for ARIA monitoring in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Real-world use of diagnostic tests for mild cognitive impairment, Alzheimer's disease, and other dementias in Medicare fee-for-service beneficiaries.Alzheimer's & dementia (Amsterdam, Netherlands)Article
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7 authors.
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Abstract
introductionThis study assessed real-world use of diagnostic tests, such as neuroimaging (e.g., magnetic resonance imaging [MRI], or positron emission tomography [PET]), and computed tomography (CT), cerebrospinal fluid (CSF) biomarker, and blood tests for mild cognitive impairment (MCI), Alzheimer's disease (AD), and other dementias in a large US elderly population.
methodsMedicare fee-for-service data (2015-2020) were used to identify patients aged ≥ 67 newly diagnosed with MCI, AD, or other dementias. Descriptive analyses were conducted to understand the test use within 1 year before disease diagnosis and trends.
resultsAmong 653,420 patients (9.1% MCI, 30.3% AD, 60.6% other dementias), 71.9% had blood tests, 53.9% neuroimaging (46.4% CT, 17.7% MRI, and 0.7% PET), and 2.2% CSF test. Test use slightly increased from 2015 to 2020. DISCUSSION: Findings from this study suggest low use of diagnostic tests, especially PET and CSF. Highlights: Blood tests, magnetic resonance imaging, and computed tomography were predominant for diagnosing mild cognitive impairment, Alzheimer's disease, or other dementias prior to the arrival of disease-modifying therapies.Cerebrospinal fluid biomarker and positron emission tomography tests were infrequently used despite their diagnostic value.The study indicates a modest increase in diagnostic test usage over 6 years between 2015 and 2020.Patients often received combined or repeated diagnostic tests.
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