Evidence map›Paper›PMID 40765872›Full record

ArticleAnnals of maxillofacial surgery

Procalcitonin Level Compared to Total White Blood Cell Count and C-reactive Protein in Maxillofacial Space Infections - A Prospective Study.

Arun Velur, Lin Jacob Varghese, Vikas Elias Kuruvila, Shuhaib Rahman, Nidhi Jenson Ukken, Biju James

Abstract read
In one paragraph

Article in Annals of maxillofacial surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arun VelurDepartment of Oral and Maxillofacial Surgery, PSM College of Dental Science and Research, Thrissur, Kerala, India.
Lin Jacob VargheseDepartment of Oral and Maxillofacial Surgery, Sree Anjaneya Institute of Dental Sciences, Kozhikode, Kerala, India.
Vikas Elias KuruvilaDepartment of Oral and Maxillofacial Surgery, PSM College of Dental Science and Research, Thrissur, Kerala, India.
Shuhaib RahmanDepartment of Public Health Dentistry, PSM College of Dental Science and Research, Thrissur, Kerala, India.
Nidhi Jenson UkkenDepartment of Oral and Maxillofacial Surgery, PSM College of Dental Science and Research, Thrissur, Kerala, India.
Biju JamesDepartment of Oral and Maxillofacial Surgery, PSM College of Dental Science and Research, Thrissur, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Orofacial space infections are potentially fatal and often need emergency medical and surgical care. Prompt diagnosis of these infections can sometimes be difficult because of diffuse swelling and trismus. Early treatment response is a key to the management and recovery. Conventional markers of infection, such as C-reactive protein (CRP) and white blood cell (WBC) counts fail to properly evaluate the progress. Procalcitonin (PCT) has high sensitivity and specificity for identifying bacterial infections and helps in treatment monitoring. Materials and Methods: After ethical committee approval, 20 cases of maxillofacial space infections who came to the Department of Oral and Maxillofacial Surgery with involvement of more than two spaces were included in the study. Demographic data and vital signs were recorded. Total WBC, CRP levels and PCT levels were measured at admission, 48 h and 96 h. The values were subjected to statistical analysis. Results: The decrease in PCT values was found to be statistically significant ( Discussion: PCT succeeds as being a promising biomarker to determine the treatment response in maxillofacial space infections and guiding antibiotic regimen accordingly.

Indexed as

Antibiotic resistancecomplete blood countC-reactive proteinmaxillofacial infectionsprocalcitonin

Identifiers

PMID40765872
PMCPMC12321168

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.