ArticlePlastic and reconstructive surgery. Global open2025
Psychosocial Impact of Postmastectomy Lymphedema Syndrome: Insights From a National Claims Database Analysis of Antidepressant Prescription Fills.
Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Postmastectomy lymphedema syndrome (PMLS) has been associated with lower quality of life due to symptoms and financial consequences. This study assessed the impact of PMLS on psychosocial well-being using antidepressant fill patterns. We hypothesized that PMLS increased the odds and duration of antidepressant fills. Methods: Mastectomy encounters in the Merative MarketScan Research Databases, 2007-2022, were extracted using Current Procedural Terminology codes. Among these, patients who developed PMLS and filled antidepressant prescriptions were identified using the Results: Of 300,075 patients meeting criteria (median [interquartile range] age, 52 [45-59] y), 24,753 (8.2%) experienced PMLS. In a multivariate regression, younger age, less recent surgical year, and higher Elixhauser Comorbidity Index scores were associated with heightened odds of PMLS ( Conclusions: Patients with PMLS were associated with increased antidepressant fills compared with those without lymphedema. Lymphedema surgery did not impact duration of postmastectomy antidepressant fills. Future studies should evaluate the longitudinal abilities of surgical interventions to ameliorate depression in patients with PMLS.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.