ArticleJBMR plus2025
Greater collagen alignment is associated with accumulation of advanced glycation endproducts in iliac trabecular bone in men and women undergoing spine fusion surgery.
Article in JBMR plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the aspects of bone that contribute to skeletal integrity is critical to screening and treatment of skeletal diseases, as well as preoperative screening for orthopedic procedures. In bone, collagen organization and structure are significant contributing factors to mechanical integrity. Despite evidence that advanced glycation endproducts (AGEs) alter collagen structure and degrade bone mechanical properties, the relationship between AGE accumulation and collagen organization has not been examined in human bone tissue. In this cohort study, we examined the relationships between fluorescent AGE (fAGE) accumulation, collagen fibril alignment, and collagen fibril density in iliac crest biopsies from men and women undergoing spine fusion surgery (
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Registered trials
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