Evidence map›Paper›PMID 40765615›Full record

ArticleFrontiers in neurology2025

Semantic intrusion errors differentiate between amnestic MCI who are plasma p-tau

Rosie E Curiel Cid, David Vaillancourt, Alexandra Ortega, Elizabeth A Crocco, Kirsten Crenshaw, Stephanie M Remedios, Breton M Asken, Melissa J Armstrong, Idaly Velez Uribe, Wei-En Wang and 8 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Cognitive dysfunction in women with theJournal of Alzheimer's disease : JAD · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Rosie E Curiel Cid1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
David Vaillancourt1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Alexandra Ortega1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Elizabeth A Crocco1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Kirsten Crenshaw1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Stephanie M RemediosCenter for Cognitive Neuroscience and Aging (CNSA), Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, United States.
Breton M Asken1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Melissa J Armstrong1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Idaly Velez Uribe1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Wei-En Wang1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Monica Rosselli1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Malek Adjouadi1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Michael Marsiske1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Warren W Barker1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Steven DeKosky1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Glenn Smith1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
Ranjan Duara1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.
David A Loewenstein1Florida Alzheimer's Disease Research Center (ADRC), Miami, FL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Semantic intrusion errors (SIEs) are associated with mild cognitive impairment (MCI) due to Alzheimer's disease (AD). It is unknown whether accounting for maximum learning capacity still leads to an increase in SIEs when elevated plasma p-tau Methods: One hundred fifty-eight older adult participants completed the Loewenstein-Acevedo Scales for Semantic Interference and Learning (LASSI-L), a sensitive cognitive challenge test designed to elicit SIEs. Of these, 108 were clinically diagnosed with amnestic MCI (aMCI). Fifty-eight individuals met or exceeded a plasma p-tau Results: After adjusting for demographic covariates and maximum learning capacity, the aMCI p-tau Conclusions: Unlike previous studies that used amyloid PET or other plasma biomarkers, individuals with aMCI p-tau

Indexed as

Alzheimer's diseaseLASSI-Lmild cognitive impairmentplasma biomarkersptau217semantic interferencesemantic intrusion errors

Identifiers

PMID40765615
PMCPMC12323714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.