Evidence map›Paper›PMID 40765603›Full record

ArticleCureus2025

Strokes and Diagnostic Dilemmas: Non-bacterial Thrombotic Endocarditis Mimicking a Flail Mitral Valve.

Ahmed K Mahmoud, Reza Arsanjani, Chadi Ayoub

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ahmed K MahmoudCardiovascular Medicine Department, Mayo Clinic, Phoenix, USA.
Reza ArsanjaniCardiovascular Medicine Department, Mayo Clinic, Phoenix, USA.
Chadi AyoubCardiovascular Medicine Department, Mayo Clinic, Phoenix, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-bacterial thrombotic endocarditis (NBTE) is a rare condition characterized by sterile vegetations on cardiac valves, commonly associated with malignancy or autoimmune disorders. These vegetations pose a significant risk of embolization, leading to adverse complications such as ischemic stroke. We present a case of a 60-year-old female initially suspected of having a brain tumor, later diagnosed with multifocal strokes due to NBTE. Initial interpretation of a flail mitral valve was subsequently revised to NBTE on further assessment, but this resulted in a delay of anticoagulation initiation. This case highlights the importance of early recognition and multidisciplinary management of NBTE to prevent recurrent embolic events, highlighting the diagnostic challenges and the role of anticoagulation in its treatment.

Indexed as

flail mitral valvenon-bacterial thrombotic endocarditistherapeutic anticoagulationtransesophageal echocardiography (tee)transthoracic echocardiography (tte)

Identifiers

PMID40765603
PMCPMC12324420

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.