Evidence map›Paper›PMID 40765593›Full record

ArticleCureus2025

Pneumorrhachis in Acute Asthma Exacerbation in an 18-Year-Old Female Patient: A Report of a Rare Case.

Omar Abdelaziz, Hashim Abid, Ado Yusuf, Nickh Uppal

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In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Omar AbdelazizInternal Medicine, Manchester University National Health Service (NHS) Foundation Trust, Manchester, GBR.
Hashim AbidInternal Medicine, Manchester University National Health Service (NHS) Foundation Trust, Manchester, GBR.
Ado YusufInternal Medicine, Manchester University National Health Service (NHS) Foundation Trust, Manchester, GBR.
Nickh UppalRadiology, Manchester University National Health Service (NHS) Foundation Trust, Manchester, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pneumorrhachis (intraspinal air) is a rare radiological finding, often associated with trauma, iatrogenic causes, or increased intrathoracic pressures. We present a case of pneumorrhachis secondary to severe asthma exacerbation, highlighting its pathophysiology and clinical implications. An 18-year-old female patient presented with a history of dry cough, chest tightness, and pain in her neck. Subsequent scans, including chest X-rays and computed tomography (CT) scans, showed a large volume pneumomediastinum and pneumorrhachis. The patient was managed conservatively with bronchodilators, corticosteroids, and supplemental oxygen, leading to the resolution of symptoms and radiographic abnormalities.  This case illustrates that pneumorrhachis can occur in asthma due to increased intrathoracic pressure, leading to air dissection into the spinal canal. Conservative management suffices in most cases, as seen here.  Pneumorrhachis should be considered in severe asthma exacerbations with pneumomediastinum, even in the absence of neurological symptoms. Early recognition and treatment of the underlying asthma are crucial to prevent complications. This case adds to the limited literature on pneumorrhachis in non-traumatic settings.

Indexed as

asthma exacerbationbarotraumapneumomediastinumpneumorrhachissubcutaneous emphysema

Identifiers

PMID40765593
PMCPMC12322184

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.