Evidence map›Paper›PMID 40765584›Full record

ArticleCureus2025

Predictive Factors of Initial Pain and Disability in Patients Presenting With Neck Pain for Rehabilitation.

Emmanouil D Kapernaros, Maria Moutzouri, Georgios Krekoukias, Nikolaos Chrysagis, George A Koumantakis

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emmanouil D KapernarosPhysiotherapy Department, School of Health and Care Sciences, University of West Attica (UNIWA), Athens, GRC.
Maria MoutzouriPhysiotherapy Department, School of Health and Care Sciences, University of West Attica (UNIWA), Athens, GRC.
Georgios KrekoukiasPhysiotherapy Department, School of Health and Care Sciences, University of West Attica (UNIWA), Athens, GRC.
Nikolaos ChrysagisLaboratory of Advanced Physiotherapy, Physiotherapy Department, School of Health and Care Sciences, University of West Attica (UNIWA), Athens, GRC.
George A KoumantakisLaboratory of Advanced Physiotherapy, Physiotherapy Department, School of Health and Care Sciences, University of West Attica (UNIWA), Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Neck pain is a complex and multifactorial condition with increasing global prevalence and a substantial impact on disability. Understanding the interplay between physical and psychological factors at the onset of rehabilitation is critical for effective, individualized care. Objective To identify physical (body weight/height, pain chronicity, physical activity, posture) and psychological (anxiety, depression, job satisfaction) predictors of pain intensity and disability in patients with neck pain presenting for physiotherapy, aiming to enhance early-stage assessment and address a research gap regarding predictors at the point of initial physiotherapy evaluation. Methods A cross-sectional cohort study was conducted involving 71 patients with neck pain attending a physiotherapy clinic. Clinical assessments and validated questionnaires were used to evaluate physical and psychological parameters, including the Neck Disability Index (NDI), Numeric Rating Scale for pain (NRS), Hospital Anxiety and Depression Scale (HADS), International Physical Activity Questionnaire (IPAQ), and the Minnesota Satisfaction Questionnaire - Short Form (MSQ-Short). Stepwise multiple regression analyses were performed to identify predictors of pain intensity and disability. Results Pain intensity was positively associated with disability (r = 0.41, p < 0.001) and depression (r = 0.27, p < 0.001), but negatively associated with anxiety (r = -0.18, p = 0.012). Disability showed strong associations with pain intensity (r = 0.41, p < 0.001), depression (r = 0.54, p < 0.001), and anxiety (r = 0.34, p < 0.001). In the multivariable analysis, lower anxiety levels significantly predicted higher pain intensity (β = -0.134, p < 0.001), an unexpected finding that may reflect coping-related mechanisms. Higher disability was predicted by greater depression (β = 0.257, p < 0.001) and lower job satisfaction (β = -0.215, p < 0.001). The models explained 37.7% of the variance in pain intensity and 49.3% in disability. Conclusion Both physical and psychological factors significantly influence pain and disability in patients with neck pain at the initial physiotherapy evaluation. Early identification of these predictors may improve clinical decision-making and rehabilitation outcomes. Future longitudinal studies in broader populations are recommended to validate these findings.

Indexed as

anxietybiopsychosocial modelcoping mechanismsdepressiondisabilityneck painpain intensityphysical activityphysiotherapypredictive factors

Identifiers

PMID40765584
PMCPMC12322511

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.