Evidence map›Paper›PMID 40765500›Full record

ArticleJournal of the American Chemical Society2025

The Action of Plastic Degrading Enzyme Is Accelerated Mainly Due to an Increase in Thermal Stability Rather Than by an Inherent Catalytic Effect.

Ashim Nandi, Arieh Warshel

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ashim NandiDepartment of Chemistry, University of Southern California, Los Angeles, California 90089-1062, United States.ORCID 0000-0002-1090-7664
Arieh WarshelDepartment of Chemistry, University of Southern California, Los Angeles, California 90089-1062, United States.ORCID 0000-0001-7971-5401

Funding

Multiscale Simulations of Biological Systems and ProcessesR35GM122472 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ARIEH WARSHEL · 2017 to 2026
$5.0M
NIGMS NIH HHS R35 GM122472
6 · The paper itself

Abstract

Polyethylene terephthalate (PET) hydrolases offer a promising enzymatic route to plastic waste degradation under mild conditions. Among these, the engineered FAST-PETase variant exhibits superior catalytic efficiency and thermostability compared to the wild-type

Indexed as

HydrolasesPolyethylene TerephthalatesTemperatureBiocatalysisEnzyme StabilityHydrolasesPolyethylene Terephthalates

Identifiers

PMID40765500
PMCPMC12396890

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.