Evidence map›Paper›PMID 40765280›Full record

ArticleGerodontology2026

Association of Tooth Loss With Stress and Depressive Symptoms in Korean Adults: An Analysis Using Korean National Health and Nutrition Examination Survey (KNHANES VI) (2013, 2015).

Jae-Hun Koh, Eun-Jae Choi, Jung-Ah Lee, Seon-Jip Kim, Hyun-Jae Cho

Abstract read
In one paragraph

Article in Gerodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jae-Hun KohDepartment of Preventive Dentistry & Public Oral Health, School of Dentistry and Dental, Research Institute, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0009-0003-1131-1445
Eun-Jae ChoiDepartment of Preventive Dentistry & Public Oral Health, School of Dentistry and Dental, Research Institute, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0009-0007-3282-0491
Jung-Ah LeeSue & Bill Gross School of Nursing, University of California, Irvine, California, USA.ORCID https://orcid.org/0000-0003-0678-5956
Seon-Jip KimDepartment of Preventive Dentistry & Public Oral Health, School of Dentistry and Dental, Research Institute, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-5909-5743
Hyun-Jae ChoDepartment of Preventive Dentistry & Public Oral Health, School of Dentistry and Dental, Research Institute, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-3079-8629

Funding

National Research Foundation of Korea(NRF) RS-2024-00407105
6 · The paper itself

Abstract

objectiveTo examine the association between tooth loss and depressive symptoms in the Korean population using nationally representative data.

backgroundTooth loss negatively impacts oral function, aesthetics, and overall quality of life. It can lead to systemic issues, such as nutritional deficiencies, and is associated with mental health problems, including depressive symptoms. While the relationship between tooth loss and depressive symptoms has been explored in Western populations, research focusing on Asian populations, particularly Koreans, remains limited. MATERIALS AND

methodsThis cross-sectional study utilised data from the 6th Korea National Health and Nutrition Examination Survey (KNHANES), including 9,166 adults aged 30 years and older. The primary variable was the number of remaining natural teeth, categorised as fewer than 12 or more. Stress and depressive symptoms were assessed using self-report questionnaires. Logistic regression models were used to evaluate the association between tooth loss and depressive symptoms after adjusting for sociodemographic, behavioural and health-related factors.

resultsAmong the 9166 participants, 946 had fewer than 12 remaining natural teeth, and the remainder had 12 or more. Participants with fewer than 12 teeth showed significantly higher adjusted odds of experiencing depressive symptoms (aOR, adjusted odds ratio, 1.45; 95% CI, confidence interval, 1.12-1.87) and stress (aOR, 1.35; 95% CI, 1.04-1.74) than those with more teeth. These associations were particularly pronounced among women, older adults (≥ 65 years), and individuals requiring dentures.

conclusionThis study demonstrates a significant association between having fewer remaining teeth and higher levels of stress and depressive symptoms, emphasising the importance of oral health in mental well-being. The relationship was particularly evident among women, younger adults and those with unmet prosthetic needs. These findings highlight the need to incorporate oral health considerations into public mental health strategies targeting high-risk populations.

Indexed as

DepressionStress, PsychologicalTooth LossAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysRepublic of KoreaKorean adultsoral healthtooth loss depressive symptoms

Identifiers

PMID40765280
PMCPMC12872974

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.