Evidence map›Paper›PMID 40765238›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Neighborhood environments and transition to cognitive states: Sydney Memory and Ageing Study.

Ester Cerin, Annabel P Matison, Miguel A Molina, Ralf-Dieter Schroers, Wei Li, Luke D Knibbs, Vibeke Sorensen Catts, Yu-Tzu Wu, Maria V Soloveva, Kaarin J Anstey and 6 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Urban greenspace and dementia: Measures, mechanisms, and methodological guidance.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  2. Driving the neural exposome: Latent mobility states from naturalistic GPS data in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Neighborhood environments and transition to cognitive states: Sydney Memory and Ageing Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ester CerinMary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia.ORCID 0000-0002-7599-165X
Annabel P MatisonCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Miguel A MolinaMary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia.
Ralf-Dieter SchroersMary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia.
Wei LiMary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia.
Luke D KnibbsSchool of Public Health, The University of Sydney, Sydney, New South Wales, Australia.
Vibeke Sorensen CattsCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Yu-Tzu WuPopulation Health Sciences Institute, Faculty of Medical Sciences, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK.
Maria V SolovevaMary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia.
Kaarin J AnsteySchool of Psychology, University of New South Wales, Kensington, New South Wales, Australia.
Suzanne MavoaPopulation Health, Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.
Govinda PoudelMary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia.
Bin JalaludinSchool of Population Health, University of New South Wales, Kensington, New South Wales, Australia.
Nicole A KochanCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Henry BrodatyCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Perminder S SachdevCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.

Funding

A global epidemiology of cognitive impairment and dementia due to Alzheimer's disease and related disorders: the COSMIC CollaborationR01AG057531 · NIA · UNIVERSITY OF NEW SOUTH WALES · PI Perminder S SACHDEV · 2023 to 2026
$5.9M
Australian Catholic University ACURF18Medical Research Council MR/T038500/ 1National Health & Medical Research Council (NHMRC) Program Grants APP1093083National Health & Medical Research Council (NHMRC) Program Grants ID350833National Health & Medical Research Council (NHMRC) Program Grants ID568969National Health and Medical Research Council 2019/ GNT1193236NIA NIH HHS R01 AG057531NIH HHS R01AG057531
6 · The paper itself

Abstract

introductionFeatures of the neighborhood environment and ambient air pollution have been associated with onset and progression of neurocognitive disorders, but data from longitudinal population-based studies are limited.

methodsOne thousand thirty-six participants (78.3 ± 4.8 years) of the Sydney Memory and Ageing Study were followed for up to 13.7 years with biennial cognitive assessments. Neighborhood environmental features were assessed around the participants' homes. Associations between environmental features and transitions to cognitive states were estimated.

resultsPopulation density, street connectivity, access to commercial services, public transport, water bodies, and tree canopy were associated with a lower likelihood of worsening cognitive state. The opposite was observed for annual average concentrations of PM DISCUSSION: Healthy neighborhood environments may delay cognitive decline and the onset of dementia in older individuals. HIGHLIGHTS: This is the first published study on neighborhood built and natural environmental correlates of transition to dementia. This study was conducted in socially advantaged areas with relatively low ambient air pollution. Walkable neighborhoods are associated with a lower likelihood of worsening cognitive state. Neighborhood tree canopy is consistently predictive of better cognitive outcomes. Access to public transport, and blue and green spaces is associated with higher probability of improved cognitive state.

Indexed as

AgingCognitionCognitive DysfunctionNeighborhood CharacteristicsResidence CharacteristicsAgedAged, 80 and overAir PollutionFemaleHumansLongitudinal StudiesMaleair pollutionblue spacebuilt environmentdementiagreen spacemild cognitive impairment

Identifiers

PMID40765238
PMCPMC12325892

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.