Evidence map›Paper›PMID 40765228›Full record

ArticleJournal of veterinary science2025

Analysis of tick-borne pathogens using next-generation sequencing in ticks from wild animals in the Republic of Korea.

Hye-Ryung Byun, Mi-Sun Rieu, Seong-Ryeong Ji, Hyun-Young Nam, Seulgi Seo, Chang-Yong Choi, Ki-Jeong Na, Jong-Taek Kim, Soyeon Cho, Bo-Yeon Hwang and 1 more

Abstract read
In one paragraph

Article in Journal of veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hye-Ryung ByunLaboratory of Veterinary Internal Medicine, BK21 FOUR Future Veterinary Medicine Leading Education and Research Center, Research Institute for Veterinary Science and College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0009-0003-2853-7109
Mi-Sun RieuArmed Forces Medical Readiness and Training School, Daejeon 34059, Korea.ORCID https://orcid.org/0009-0008-4424-5348
Seong-Ryeong JiLaboratory of Veterinary Internal Medicine, BK21 FOUR Future Veterinary Medicine Leading Education and Research Center, Research Institute for Veterinary Science and College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0009-0006-6618-4393
Hyun-Young NamSchool of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0000-0002-2701-7713
Seulgi SeoResearch Institute of Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0009-0006-3268-2669
Chang-Yong ChoiResearch Institute of Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0000-0002-4519-7957
Ki-Jeong NaLaboratory of Veterinary Laboratory and Wildlife Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0001-6076-3147
Jong-Taek KimCollege of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0002-6388-550X
Soyeon ChoBird Research Center, Korea National Park Research Institute, Shinan 58863, Korea.ORCID https://orcid.org/0009-0007-5366-9452
Bo-Yeon HwangBird Research Center, Korea National Park Research Institute, Shinan 58863, Korea.ORCID https://orcid.org/0000-0002-4037-0765
Joon-Seok ChaeLaboratory of Veterinary Internal Medicine, BK21 FOUR Future Veterinary Medicine Leading Education and Research Center, Research Institute for Veterinary Science and College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea. jschae@snu.ac.kr.ORCID https://orcid.org/0000-0002-4813-3342

Funding

Ministry of Agriculture, Food and Rural Affairs 122062-2
6 · The paper itself

Abstract

importanceClimate and anthropogenic changes have resulted in the growth of tick populations and tick-borne pathogens worldwide. Standardized surveillance systems are essential for novel tick-borne pathogens in the Republic of Korea (ROK). Analysis of blood-fed ticks suggests that zoonotic pathogens have the potential to circulate between ticks and wild animals in natural environments.

objectiveThis study aimed to analyze blood-fed ticks from wild animals in the ROK and detect novel tick-borne pathogens in the ROK to develop effective surveillance systems and preventive strategies.

methodsNext-generation sequencing (NGS) identified 217 ticks with eight pooled samples collected from five wild mammals and 22 birds in five wildlife rescue centers and three bird banding stations in the ROK from February 2022 to May 2023.

resultsAfter NGS, clean reads of 17,017,249-32,372,003 viruses, 116,996-289,716 bacteria, and 164,462-352,826 protozoa were obtained in each region. Several pathogens, including those in families such as CONCLUSIONS AND RELEVANCE: This study suggests that tick-borne zoonotic pathogens can circulate in ticks and animals and have potential transmission effects in humans. Hence, wild animals, including mammals and birds, may serve as reservoirs of zoonotic infection carriers.

Indexed as

Animals, WildMammalsTick-Borne DiseasesTicksAnimalsBacteriaBird DiseasesBirdsHigh-Throughput Nucleotide SequencingRepublic of KoreaNext-generation sequencingpublic healthtick-borne diseasestickszoonoses

Identifiers

PMID40765228
PMCPMC12329051

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.