ArticlePhysical activity and nutrition2025
Effects of rice protein hydrolysate on bone fracture properties in ovariectomized rats.
Article in Physical activity and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
purposeOsteoporosis is a global health concern, particularly in developed countries with aging populations, where the incidence of postmenopausal osteoporosis is increasing. Various nutrients have been studied as potential interventions, and components derived from regionally familiar foods may enhance acceptability and adherence. In this study, we focused on rice, a staple food in Asia and Africa. Recent studies have suggested that rice-derived peptides may help prevent bone fragility. Therefore, we examined the effects of rice protein hydrolysate (RPH) on bone health in ovariectomized rats.
methodsIn Study 1, which was designed to prevent osteoporosis, 5-week-old female Sprague-Dawley rats were acclimated for one week and then underwent ovariectomy (OVX). They were divided into three groups: a control group fed a normal diet and two experimental groups fed diets containing 0.01% or 0.1% RPH for eight weeks. In Study 2, which aimed at promoting recovery from osteoporosis, the setup was similar; however, after OVX, rats were fed a low-calcium diet for four weeks to induce osteoporosis, followed by the same diet groups as in Study 1 for an additional four weeks.
resultsStudy 1 showed that RPH significantly increased bone-breaking force (0.01% RPH, p < 0.01; 0.1% RPH, p < 0.05). In Study 2, RPH intake reduced serum tartrate-resistant acid phosphatase (TRAP) levels, a marker of bone resorption (both p < 0.05). However, a significant effect on bone mineral density was observed only in the 0.01% RPH group in Study 1 (p < 0.05).
conclusionThese findings suggested that RPH may help treat postmenopausal osteoporosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.