ArticleEuropean journal of medical research2025
Efficacy of a modified cranial closure technique with bone cement in reducing postoperative complications following microvascular decompression surgery: a retrospective cohort study.
Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThis study aimed to assess the efficacy of a modified cranial closure technique combined with bone cement in mitigating postoperative complications, particularly cerebrospinal fluid (CSF) leakage, following microvascular decompression (MVD) surgery.
methodsA retrospective analysis was conducted on 234 patients who underwent MVD surgery at our institution from October 2017 to October 2024. The patients were divided into three groups based on closure methods: autologous bone with bone cement and titanium screw and plate (ABBC + TSP), autologous bone with bone cement (ABBC), and traditional cranial closure (TCC). Postoperative complications, including CSF leakage, intracranial infection, and subcutaneous effusion, were compared among the groups.
resultsThe incidence of CSF leakage was significantly lower in the modified groups (ABBC + TSP and ABBC) compared to the traditional group (2.5% and 1.8 vs. 27.0%, P < 0.001). Multivariate logistic regression analysis confirmed that the modified technique was an independent protective factor against CSF leakage (OR 0.138, p = 0.024). Additionally, the modified groups demonstrated significantly lower rates of intracranial infection, subcutaneous effusion, and postoperative headache (p < 0.05).
conclusionThe modified cranial closure technique combined with bone cement significantly reducing postoperative complications in MVD surgery, particularly CSF leakage and intracranial infection, presenting a promising approach for optimizing surgical outcomes.
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