Evidence map›Paper›PMID 40764991›Full record

ArticleBMC medicine2025

The global burden of disease attributable to suboptimal fruit and vegetable intake, 1990-2021: a systematic analysis of the global burden of disease study.

Xiang Xu, Pengguang Yan, Wenjin Chen, Wei Wei, Blake Thomson, Shuaizhi Ruan, Zhong Cao, Chengzhu Ou, Pascal Geldsetzer, Taotao Han and 3 more

Abstract read
In one paragraph

Article in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiang Xu *Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Pengguang Yan *Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Wenjin ChenSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wei WeiDepartment of Clinical Nutrition, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Blake ThomsonSurveillance and Health Equity Science, American Cancer Society, Atlanta, GA, USA.
Shuaizhi RuanDepartment of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Zhong CaoState Key Lab of Intelligent Technologies and Systems, Beijing National Research Center for Information Science and Technology, Department of Automation, Tsinghua University, Beijing, China.
Chengzhu OuDepartment of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Pascal GeldsetzerDivision of Primary Care and Population Health, Department of Medicine, Stanford University, Palo Alto, CA, USA.
Taotao HanDepartment of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Jing WangDepartment of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Simiao ChenSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. simiao.chen@uni-heidelberg.de.
Jingnan LiDepartment of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. lijn2008@126.com.

Funding

National High Level Hospital Clinical Research Funding No. 2022-PUMCH-B-022National Natural Science Foundation of China Grant No. 82400638
6 · The paper itself

Abstract

backgroundSuboptimal fruit and vegetable intake remains a significant global public health concern. This study aimed to estimate the global intake and the disease burden attributable to suboptimal fruit and vegetable intake.

methodsIn this Global Burden of Disease (GBD) Study 2021, we evaluated the number, age-standardized rates (ASRs), and estimated annual percentage changes (EAPCs) in deaths and disability-adjusted life years (DALYs) attributable to suboptimal fruit and vegetable intake among adults aged over 25 years, across 21 regions and 204 countries and territories, from 1990 to 2021.

resultsIn 2021, the global average intake of fruit and vegetable was 121.8 g/day and 212.6 g/day, respectively, far below the optimal intake range (fruit: 340-350 g/day, vegetable: 306-372 g/day). Suboptimal consumption contributed to 1.7 million (95% uncertainty interval [UI] 0.8 to 2.5, fruit) and 0.9 million (95% UI 0.5 to 1.2, vegetable) deaths globally, with cardiovascular diseases accounting for 83.7% (ASR 16.80/100,000) and 79.3% (ASR 8.22/100,000) of mortality attributable to suboptimal fruit and vegetable intake, respectively. Between 1990 and 2021, age-standardized mortality rates decreased by 35% (95%UI 28% to 40%) for fruit and 45% (95% UI 38% to 50%) for vegetables. The global disease burden attributable to suboptimal fruit and vegetable intake was inversely associated with sociodemographic index (SDI) and human development index (HDI). Over three decades, the difference in fruit (52.0 vs. 84.4 g/day) and vegetable (125.5 vs. 158.5 g/day) intake between higher (high, high-middle, middle) and lower (low-middle, low) SDI regions increased by 62.3% and 26.3%, respectively. Meanwhile, disparities in disease burden also increased, as higher SDI regions experienced greater reductions in age-standardized mortality due to suboptimal fruit (- 47.0% vs. - 17.7%) and vegetable (- 58.8% vs. - 26.8%) intake, highlighting widening health inequities linked to developmental disparities.

conclusionsSuboptimal fruit and vegetable intake continues to contribute to a substantial and unequal global disease burden. Reducing this burden should be a global priority, particularly in regions with low SDI and HDI.

Indexed as

DietFruitGlobal Burden of DiseaseVegetablesAdultAgedDisability-Adjusted Life YearsFemaleGlobal HealthHumansMaleMiddle AgedDisease burdenGlobal burden of disease study 2021Suboptimal fruit and vegetable intake

Identifiers

PMID40764991
PMCPMC12326680

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.