Evidence map›Paper›PMID 40764917›Full record

ArticleBMC primary care2025

Point-of-care ultrasonography of carotid arteries in primary care: sensitivity and specificity of identification of carotid atherosclerosis and prevalence of carotid atherosclerosis in apparently healthy subjects with high and very high cardiovascular disease risk.

Anej Kebrič, Marija Petek Šter, Anja Poljanšek Avsenak, Borut Jug

Abstract read
In one paragraph

Article in BMC primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anej KebričDiagnostični Center Šentjur, Ulica Dušana Kvedra 27, Šentjur, 3230, Slovenia. anej.kebric@gmail.com.
Marija Petek ŠterFaculty of Medicine, Department of Family Medicine, University of Ljubljana, Poljanski nasip 58, Ljubljana, 1000, Slovenia.
Anja Poljanšek AvsenakFaculty of Medicine, Department of Family Medicine, University of Ljubljana, Poljanski nasip 58, Ljubljana, 1000, Slovenia.
Borut JugDepartment of Vascular Diseases, University Medical Centre Ljubljana, Zaloška cesta 7, Ljubljana, 1000, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular diseases (CVDs) remain a major global health concern, contributing significantly to morbidity and mortality. The use of point-of-care ultrasonography (POCUS) in primary care has grown in popularity, offering a promising approach for early atherosclerosis detection. The objective was to investigate the sensitivity and specificity of family medicine physicians in identifying carotid atherosclerosis using POCUS and to determine the prevalence of carotid atherosclerosis in apparently healthy subjects with high or very high CVD risk.

methodsA cross-sectional study was conducted from June 2023 to January 2024 across seven family medicine practices in Slovenia. The study included 199 participants aged 40-69, with high or very high CVD risk and no prior treatment with antilipemic drugs. Two participants were excluded due to insufficient quality of ultrasonographic recordings. Participants underwent POCUS of the carotid arteries to detect atherosclerotic plaques. Sensitivity and specificity were calculated against the assessments of a certified specialist in cardiology and vascular medicine.

resultsThe study found a high prevalence (69.5% [62.6-75.9]) of carotid atherosclerosis among participants, with higher rates in males and older age groups. Sensitivity and specificity of POCUS for detecting carotid atherosclerosis were 96.4% [91.7-98.8] and 90.0% [79.5-96.2], respectively. Carotid atherosclerosis was more common in participants with very high CVD risk compared to those with high CVD risk.

conclusionsCarotid atherosclerosis in apparently healthy subjects with high and very high CVD risk is much more prevalent than expected. POCUS of the carotid arteries is a highly sensitive and specific method for detecting carotid atherosclerosis in primary care. This method can significantly enhance early CVD risk assessment and intervention by family medicine practitioners.

trial registrationISRCTN registry as ISRCTN10591599 (registration date 26.07.2024).

Indexed as

Carotid ArteriesCarotid Artery DiseasesPoint-of-Care SystemsAdultAgedCardiovascular DiseasesCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalencePrimary Health CareSensitivity and SpecificitySloveniaUltrasonographyCarotid artery POCUSCVD riskFamily medicinePOCUSPrevalencePrimary careSensitivity and specificity

Identifiers

PMID40764917
PMCPMC12326624

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.