Evidence map›Paper›PMID 40764911›Full record

ArticleBMC public health2025

Public health surveillance of tropical diseases in Madagascar: a scoping review of population burden, intervention strategies, and health system responses.

Mamy Jayne Nelly Rajaofera, Wei Liu, Sylvana Tomboanona, Alphonsine Mboty Reziky, Dai Kuang, Qianfeng Xia

Abstract readScoping Review
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Integrated Malaria Control in Madagascar: From Vector Dynamics to Community Interventions.The American journal of tropical medicine and hygiene · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mamy Jayne Nelly Rajaofera *NHC Key Laboratory of Tropical Disease Control, School of Tropical Medicine, Hainan Medical University, Haikou, Hainan, 571199, China.
Wei Liu *NHC Key Laboratory of Tropical Disease Control, School of Tropical Medicine, Hainan Medical University, Haikou, Hainan, 571199, China.
Sylvana TomboanonaÉcole Doctorale Écosystèmes Naturels, Université de Mahajanga, Mahajanga, 401, Madagascar.
Alphonsine Mboty RezikyÉcole Doctorale Nutrition-Environnement-Santé (EDNES, Université de Mahajanga, Mahajanga, 401, Madagascar.
Dai KuangNHC Key Laboratory of Tropical Disease Control, School of Tropical Medicine, Hainan Medical University, Haikou, Hainan, 571199, China. kuangdai1989@163.com.
Qianfeng XiaNHC Key Laboratory of Tropical Disease Control, School of Tropical Medicine, Hainan Medical University, Haikou, Hainan, 571199, China. xiaqianfeng@hainmc.edu.cn.

Funding

Major Science and Technology Program of Hainan Province ZDKJ202003
6 · The paper itself

Abstract

backgroundMadagascar faces unique challenges in tropical disease management due to its diverse geography, tropical climate, and socioeconomic factors. This review examines current challenges in tropical medicine in Madagascar and explores opportunities for improving public health outcomes, with a focus on six priority diseases.

methodsWe conducted a comprehensive scoping review of literature published between January 2000 and December 2024, searching PubMed, Google Scholar, ScienceDirect, and Web of Science. Studies were included if they reported on tropical disease burden, interventions, health outcomes, or health system capacity in Madagascar. Studies were excluded if they were not available in English or French, lacked Madagascar-specific focus, did not discuss health systems or population-level disease control, focused solely on laboratory techniques without public health relevance, were conference abstracts or reports without full-text availability, or came from non-credible sources. Peer-reviewed literature was supplemented with grey literature. Data were extracted using a standardized form by two independent reviewers and analyzed thematically.

resultsMadagascar shows divergent disease patterns compared to regional averages. Malaria represents the biggest concern, with cases up 132% and deaths up 278% by 2023, now exceeding regional rates. Conversely, lymphatic filariasis represented a remarkable public health success, achieving 93% prevalence reduction and slightly outperforming regional outcomes. Dengue control remained exemplary throughout the study period, with Madagascar maintaining rates approximately three times lower than regional averages. Leprosy burden persistently exceeded regional averages by threefold despite achieving 54% reduction, while tuberculosis and schistosomiasis follow continental reduction trends. Control strategies included integrated vector management, mass drug administration achieving 76.3% national coverage for lymphatic filariasis, seasonal malaria chemoprevention, and targeted treatment approaches. Disease spread is driven by poor infrastructure, poverty, water access issues, and favorable climate. Research gaps exist in disease interactions, economic impact, and intervention acceptance.

conclusionAddressing tropical disease burden in Madagascar requires strengthened public health infrastructure, increased domestic health financing, improved health workforce retention, and targeted interventions for remote communities. Building local research capacity, investing in innovative technologies, and implementing integrated disease control approaches are essential for improving population health outcomes.

Indexed as

Public Health SurveillanceTropical MedicineCost of IllnessHumansMadagascarDisease control programsHealth systems strengtheningMadagascarPopulation healthPublic healthTropical diseases

Identifiers

PMID40764911
PMCPMC12326601

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.